Evidence map›Paper›PMID 32946786›Full record

ArticleCell2020

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.

Christoph Kreer, Matthias Zehner, Timm Weber, Meryem S Ercanoglu, Lutz Gieselmann, Cornelius Rohde, Sandro Halwe, Michael Korenkov, Philipp Schommers, Kanika Vanshylla and 18 more

2 registry-linked trialsAbstract readPublished Erratum
In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04631666 phase1 / phase2completednot on this map

A Phase 1/2a Trial of the Intravenous Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c in SARS-CoV-2-Infected and -Uninfected Individuals

TypeinterventionalSponsorUniversity of CologneRan2020 to 2021Enrolled57ConditionsSARS-CoV-2 InfectionArmsDZIF-10c, Placebo
NCT04631705 phase1 / phase2terminatednot on this map

A Phase 1/2a Trial of the Inhaled Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c in SARS-CoV-2-Infected and -Uninfected Individuals

TypeinterventionalSponsorUniversity of CologneRan2020 to 2021Enrolled45ConditionsSARS-CoV-2 InfectionArmsDZIF-10c, Placebo
3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Recombinant neutralizing secretory IgA antibodies for preventing mucosal acquisition and transmission of SARS-CoV-2.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Christoph Kreer
Matthias Zehner
Timm Weber
Meryem S Ercanoglu
Lutz Gieselmann
Cornelius Rohde
Sandro Halwe
Michael Korenkov
Philipp Schommers
Kanika Vanshylla
Veronica Di Cristanziano
Hanna Janicki
Reinhild Brinker
Artem Ashurov
Verena Krähling
Alexandra Kupke
Hadas Cohen-Dvashi
Manuel Koch
Jan Mathis Eckert
Simone Lederer
Nico Pfeifer
Timo Wolf
Maria J G T Vehreschild
Clemens Wendtner
Ron Diskin
Henning Gruell
Stephan Becker
Florian Klein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32946786
PMCPMC7497397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.