Evidence map›Paper›PMID 32946760›Full record

ArticleMolecular cell2020

PARP-1 Flips the Epigenetic Switch on Obesity.

Carla E Margulies, Andreas G Ladurner

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Carla E MarguliesBiomedical Center, Department of Molecular Biology, Ludwig-Maximilians-University Munich, Grosshaderner Strasse 9, 82152 Planegg, Germany.
Andreas G LadurnerBiomedical Center, Department of Physiological Chemistry, Ludwig-Maximilians-University Munich, Grosshaderner Strasse 9, 82152 Planegg, Germany; Eisbach Bio GmbH, Am Klopferspitz 19, 82152 Planegg, Germany. Electronic address: andreas.ladurner@bmc.med.lmu.de.
Eisbach Bio (Germany) · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PARP enzymes are increasingly taking on important roles beyond DNA repair. Huang et al. (2020b) report how the NAD

Indexed as

HistonesPoly(ADP-ribose) Polymerase InhibitorsAdipogenesisADP-RibosylationEpigenesis, GeneticHumansObesityPhosphorylationPoly(ADP-ribose) PolymerasesHistonesPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) Polymerases

Identifiers

PMID32946760
OpenAlexW3087580806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.