ArticleCurrent biology : CB2020
The Dorsal Striatum Energizes Motor Routines.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 67 citations in OpenAlex.
- Continuous contributions of the dorsolateral striatum to movement initiation and execution.Science advances · 2026Article
- Striatal pathways dissociably control action counting and goal-directed steering.Nature neuroscience · 2026Article
- The Tower Foraging Park: A paradigm for studying cognitive and motor processes underlying behavioral flexibility in freely moving mice.iScience · 2026Article
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- A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia.Brain : a journal of neurology · 2026Article
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- Rapid dopaminergic signatures in movement: Reach vigor reflects reward prediction error and learned expectation.Science advances · 2026Article
- Differential cannabinergic effects on temporal perception and production.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Deletion of Glutamate Delta 1 Receptor Leads to Heterogeneous Transcription and Synaptic Gene Alterations Across Brain Regions.International journal of molecular sciences · 2025Article
- Decoding auditory cognition: Unraveling the corticostriatal-SNr circuit's role in frequency discrimination accuracy.iScience · 2025Article
- Neurodegenerative Disease Movement Disorders and Dorsal Striatum-Mediated Imbalance of Habitual Motor Sequences.Molecular neurobiology · 2025Review
- Striatal Pathways for Action Counting and Steering.bioRxiv : the preprint server for biology · 2025Article
- Dissociable habits of response preparation versus response initiation.Nature human behaviour · 2025Article
- Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement.Nature neuroscience · 2025Article
- Rapid Dopaminergic Signatures in Movement: Reach Vigor Reflects Reward Prediction Error and Learned Expectation.bioRxiv : the preprint server for biology · 2025Article
- Reliability of Brain Activity During a Supine Bilateral Leg Press and Association With Concurrent 3D Knee Joint Biomechanics.The European journal of neuroscience · 2025Article
- The Role of Striatum in Controlling Waiting during Reactive and Self-Timed Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- PathogenicLife science alliance · 2025Article
- Article
- Adaptation of sequential action benefits from timing variability related to lateral basal ganglia circuitry.iScience · 2024Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dorsal striatum (dS) has been implicated in storing procedural memories and controlling movement kinematics. Since procedural memories are expressed through movements, the exact nature of the dS function has proven difficult to delineate. Here, we challenged rats in complementary locomotion-based tasks designed to alleviate this confound. Surprisingly, dS lesions did not impair the rats' ability to remember the procedure for the successful completion of motor routines. However, the speed and initiation of the reward-oriented phase of the routines were irreversibly altered by the dS lesion. Further behavioral analyses, combined with modeling in the optimal control framework, indicated that these kinematic alterations were well explained by an increased sensitivity to effort. Our work provides evidence supporting a primary role of the dS in modulating the kinematics of reward-oriented actions, a function that may be related to the optimization of the energetic costs of moving.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.