Evidence map›Paper›PMID 32946725›Full record

ArticleEmerging infectious diseases2020

Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-2018

Melanie Stecher, Antoine Chaillon, Christoph Stephan, Elena Knops, Niko Kohmer, Clara Lehmann, Josef Eberle, Johannes Bogner, Christoph D Spinner, Anna Maria Eis-Hübinger and 6 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Melanie Stecher
Antoine Chaillon
Christoph Stephan
Elena Knops
Niko Kohmer
Clara Lehmann
Josef Eberle
Johannes Bogner
Christoph D Spinner
Anna Maria Eis-Hübinger
Jan-Christian Wasmuth
Guido Schäfer
Georg Behrens
Sanjay R Mehta
Jörg Janne Vehreschild
Martin Hoenigl

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Perception of repeated negative HIV test results in young men who have sex with menR21MH113477 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOENIGL, MARTIN · 2018 to 2019
$441k
The Prostate as a Reservoir for Residual ReplicationR21AI131971 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHAILLON, ANTOINE · 2018 to 2019
$432k
NIAID NIH HHS P30 AI036214NIAID NIH HHS R21 AI131971NIAID NIH HHS R24 AI106039NIMH NIH HHS R21 MH113477
6 · The paper itself

Abstract

We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.

Indexed as

Anti-HIV AgentsHIV-1HIV InfectionsDrug Resistance, ViralGenotypeGermanyHumansMutationPhylogenyAnti-HIV Agentsantimicrobial resistanceantiretroviral therapyARTGermanyHIV transmissionmutationsphylogenetic analysispublic health

Identifiers

PMID32946725
PMCPMC7510719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.