Evidence map›Paper›PMID 32946595›Full record

ArticleInternational journal of cosmetic science2021

Penetration of different molecular weight hydrolysed keratins into hair fibres and their effects on the physical properties of textured hair.

E Malinauskyte, R Shrestha, P A Cornwell, S Gourion-Arsiquaud, M Hindley

Open access · hybridAbstract read
In one paragraph

Article in International journal of cosmetic science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Bio-active designed peptide for hair keratin strengthening.International journal of cosmetic science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

E MalinauskyteTRI Princeton, 601 Prospect Avenue, Princeton, NJ, 08540, USA.ORCID https://orcid.org/0000-0002-7828-9639
R ShresthaTRI Princeton, 601 Prospect Avenue, Princeton, NJ, 08540, USA.
P A CornwellTRI Princeton, 601 Prospect Avenue, Princeton, NJ, 08540, USA.ORCID https://orcid.org/0000-0002-4353-805X
S Gourion-ArsiquaudTRI Princeton, 601 Prospect Avenue, Princeton, NJ, 08540, USA.
M HindleyCroda Europe Ltd, Foundry Lane, Widnes, WA8 8UB, UK.
Princeton University · USCroda (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of different molecular weight (MW), wool derived hydrolysed keratins (i.e. peptides) on the physical properties of relaxed textured hair.

methodsVery curly hair of African origin was relaxed using sodium hydroxide-based treatment. Relaxed hair was treated with different MW peptides derived from keratin protein and an amino acid, L-Leucine. The low-MW keratin peptides were 221 Da, the mid-MW keratin peptides were approximately 2577 Da, and the high-MW keratin peptides were approximately 75 440 Da. The penetration of these different peptides into relaxed hair was evaluated using a laser scanning micrometre and by fluorescence microscopy. The effect of these compounds on single-fibre mechanical properties and thermal properties was evaluated using tensile and DSC testing, respectively.

resultsLow- and mid-MW compounds were able to penetrate deep into the hair cortex. High-MW peptide adsorbed onto the hair surface and possibly slightly penetrated into the outer layers of the fibre surface. Both mid- and high-MW keratin peptides, increased Young's modulus and reduced hair breakage at 20% and 80% relative humidity. With the exception of mid-MW peptide, other peptides and amino acid were not able to modify thermal properties of relaxed textured hair.

conclusionsOur data suggest that low-MW compounds may increase hair volume, and high-MW peptides may repair damage on freshly relaxed textured hair.

Indexed as

HairHumansHydrolysisKeratinsMicroscopy, Electron, ScanningMolecular WeightPeptidesSurface PropertiesKeratinsPeptideshair treatmenthydrolysed proteinkeratinpenetrationpeptidetensile propertiestextured hair

Identifiers

PMID32946595
PMCPMC7820954
OpenAlexW3087093704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.