Evidence map›Paper›PMID 32946403›Full record

ArticleIEEE journal of biomedical and health informatics2021

Wearables and Deep Learning Classify Fall Risk From Gait in Multiple Sclerosis.

Brett M Meyer, Lindsey J Tulipani, Reed D Gurchiek, Dakota A Allen, Lukas Adamowicz, Dale Larie, Andrew J Solomon, Nick Cheney, Ryan S McGinnis

Open access · greenAbstract read
In one paragraph

Article in IEEE journal of biomedical and health informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Artificial Intelligence and Multiple Sclerosis.Current neurology and neuroscience reports · 2024
    Review
  11. Assessing Free-Living Postural Sway in Persons With Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Digital Phenotypes of Instability and Fatigue Derived From Daily Standing Transitions in Persons With Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Advancing Digital Medicine with Wearables in the Wild.Sensors (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brett M Meyer
Lindsey J Tulipani
Reed D Gurchiek
Dakota A Allen
Lukas Adamowicz
Dale Larie
Andrew J Solomon
Nick Cheney
Ryan S McGinnis
University of Vermont · US

Funding

Just-In-Time Fall Prevention: Development of an mHealth Intervention for Persons with Multiple SclerosisR21EB027852 · NIBIB · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MCGINNIS, RYAN S. · 2019 to 2021
$610k
NIBIB NIH HHS R21 EB027852
6 · The paper itself

Abstract

Falls are a significant problem for persons with multiple sclerosis (PwMS). Yet fall prevention interventions are not often prescribed until after a fall has been reported to a healthcare provider. While still nascent, objective fall risk assessments could help in prescribing preventative interventions. To this end, retrospective fall status classification commonly serves as an intermediate step in developing prospective fall risk assessments. Previous research has identified measures of gait biomechanics that differ between PwMS who have fallen and those who have not, but these biomechanical indices have not yet been leveraged to detect PwMS who have fallen. Moreover, they require the use of laboratory-based measurement technologies, which prevent clinical deployment. Here we demonstrate that a bidirectional long short-term (BiLSTM) memory deep neural network was able to identify PwMS who have recently fallen with good performance (AUC of 0.88) based on accelerometer data recorded from two wearable sensors during a one-minute walking task. These results provide substantial improvements over machine learning models trained on spatiotemporal gait parameters (21% improvement in AUC), statistical features from the wearable sensor data (16%), and patient-reported (19%) and neurologist-administered (24%) measures in this sample. The success and simplicity (two wearable sensors, only one-minute of walking) of this approach indicates the promise of inexpensive wearable sensors for capturing fall risk in PwMS.

Indexed as

Deep LearningMultiple SclerosisWearable Electronic DevicesAccidental FallsGaitHumansProspective StudiesRetrospective StudiesWalking

Identifiers

PMID32946403
PMCPMC8221405
OpenAlexW3087099853

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.