Evidence map›Paper›PMID 32946314›Full record

ArticleHuman vaccines & immunotherapeutics2021

Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence.

Domenico Martinelli, Francesca Fortunato, Federico Marchetti, Rosa Prato

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Domenico MartinelliDipartimento di Scienze Mediche e Chirurgiche, Università di Foggia, Foggia, Italy.ORCID 0000-0001-8028-3167
Francesca FortunatoDipartimento di Scienze Mediche e Chirurgiche, Università di Foggia, Foggia, Italy.ORCID 0000-0003-0665-5385
Federico MarchettiMedical Department, GSK, Verona, Italy.ORCID 0000-0001-6435-8990
Rosa PratoDipartimento di Scienze Mediche e Chirurgiche, Università di Foggia, Foggia, Italy.ORCID 0000-0001-8138-5835
University of Foggia · ITGlaxoSmithKline (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acceptance of rotavirus (RV) vaccination may be impacted by several factors including the feasibility of the full schedule administration within the fixed immunization timelines. The human RV vaccine Rotarix (GSK) and the human bovine reassortant vaccine RotaTeq (Merck & Co.) were developed with different posologies (2 doses vs 3 doses respectively), which have both scientific and technical implications. A non-systematic literature review revealed that, in the Italian context, topics such as time to achieve RV protection in children, number of preventable cases and administration time window, compatibility/ease of inclusion in the national vaccination calendar, potential overlaps with the peak of natural history of intussusception and adherence to posology could be impacted by the RV vaccine posology. Results suggest that a shorter schedule would allow for greater flexibility of use as well as a greater documented ease of inclusion in the vaccination calendar, thereby reducing potential direct healthcare costs.

Indexed as

RotavirusRotavirus InfectionsRotavirus VaccinesAnimalsCattleChildHumansInfantItalyVaccinationVaccines, AttenuatedRotavirus VaccinesVaccines, Attenuatedadherenceadministrationchildrencompliancegastro-enteritisItalypediatric vaccinationRotavirusschedulevaccine

Identifiers

PMID32946314
PMCPMC8078726
OpenAlexW3087719338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.