Evidence map›Paper›PMID 32945913›Full record

ArticleNeuroradiology2021

Simultaneous time of flight-MRA and T2* imaging for cerebrovascular MRI.

Bryan A Lanzman, Yuhao Huang, Edward H Lee, Michael Iv, Michael E Moseley, Samantha J Holdsworth, Kristen W Yeom

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Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Bryan A LanzmanDepartment of Radiology, Stanford University, Stanford, CA, USA.
Yuhao HuangDepartment of Neurosurgery, Stanford University, Stanford, CA, USA.
Edward H LeeDepartment of Radiology, Stanford University, Stanford, CA, USA.
Michael IvDepartment of Radiology, Stanford University, Stanford, CA, USA.
Michael E MoseleyDepartment of Radiology, Stanford University, Stanford, CA, USA.
Samantha J HoldsworthMātai Medical Research Institute, Gisborne-Tairāwhiti, Gisborne, New Zealand.
Kristen W YeomDepartment of Radiology, Stanford University, Stanford, CA, USA. kyeom@stanford.edu.ORCID http://orcid.org/0000-0001-9860-3368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose3D multi-echo gradient-recalled echo (ME-GRE) can simultaneously generate time-of-flight magnetic resonance angiography (pTOF) in addition to T2*-based susceptibility-weighted images (SWI). We assessed the clinical performance of pTOF generated from a 3D ME-GRE acquisition compared with conventional TOF-MRA (cTOF).

methodsEighty consecutive children were retrospectively identified who obtained 3D ME-GRE alongside cTOF. Two blinded readers independently assessed pTOF derived from 3D ME-GRE and compared them with cTOF. A 5-point Likert scale was used to rank lesion conspicuity and to assess for diagnostic confidence.

resultsAcross 80 pediatric neurovascular pathologies, a similar number of lesions were reported on pTOF and cTOF (43-40%, respectively, p > 0.05). Rating of lesion conspicuity was higher with cTOF (4.5 ± 1.0) as compared with pTOF (4.0 ± 0.7), but this was not significantly different (p = 0.06). Diagnostic confidence was rated higher with cTOF (4.8 ± 0.5) than that of pTOF (3.7 ± 0.6; p < 0.001). Overall, the inter-rater agreement between two readers for lesion count on pTOF was classified as almost perfect (κ = 0.98, 96% CI 0.8-1.0).

conclusionsIn this study, TOF-MRA simultaneously generated in addition to SWI from 3D MR-GRE can serve as a diagnostic adjunct, particularly for proximal vessel disease and when conventional TOF-MRA images are absent.

Indexed as

Cerebrovascular DisordersMagnetic Resonance AngiographyMagnetic Resonance ImagingChildHumansRetrospective StudiesMRIMulti-echo gradient-recalled EchoNeurovascularPediatricTime-of-flight magnetic resonance angiography

Identifiers

PMID32945913

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.