Evidence map›Paper›PMID 32945721›Full record

ArticleNutritional neuroscience2022

Prevention and mitigation of alcohol-induced neuroinflammation by

Pradeep K Shukla, Avtar S Meena, RadhaKrishna Rao

Open access · greenAbstract read
In one paragraph

Article in Nutritional neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  5. Frontiers in neuroscience · 2022
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pradeep K ShuklaDepartment of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0003-2515-9766
Avtar S MeenaDepartment of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA.
RadhaKrishna RaoDepartment of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0002-5906-8371
University of Tennessee Health Science Center · US

Funding

INTESTINAL MUCOSAL PROTECTION BY EPIDERMAL GROWTH FACTORR01DK055532 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RAO, RADHAKRISHNA · 1998 to 2020
$4.7M
MECHANISM OF ENDOTOXIN ABSORPTION IN ALCOHOLISMR01AA012307 · NIAAA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RAO, RADHAKRISHNA · 2000 to 2014
$3.9M
Defining the Role of Intestinal Calcium Channels in Alcoholic Liver Damage.R01AA029270 · NIAAA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RADHAKRISHNA RAO · 2022 to 2026
$2.5M
Intestinal Mucosal Protection by Epidermal Growth FactorR56DK055532 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RAO, RADHAKRISHNA · 2009 to 2009
$345k
Impact of Stress on Alcoholic Gut InjuryI01BX003014 · VA · MEMPHIS VA MEDICAL CENTER · PI RADHAKRISHNA RAO · 2017 to 2026
–
BLRD VA I01 BX003014NIAAA NIH HHS R01 AA012307NIAAA NIH HHS R01 AA029270NIDDK NIH HHS R01 DK055532NIDDK NIH HHS R56 DK055532
6 · The paper itself

Abstract

Neuroinflammation is implicated in the pathogenesis of alcohol use disorders. We investigated the role of Gut-Brain interactions in alcohol-induced neuroinflammation by probiotic-mediated manipulation of intestinal dysbiosis in mice. Chronic ethanol feeding induced dysbiosis, as evidenced by an increase in Firmicutes/Bacteroidetes ratio and depletion of

Indexed as

AlcoholismLactiplantibacillus plantarumAnimalsErbB ReceptorsEthanolMiceNeuroinflammatory DiseasesErbB ReceptorsEthanolalcohol use disorderDysbiosisethanolmicrogliaprobiotic

Identifiers

PMID32945721
PMCPMC7969470
OpenAlexW3087007401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.