Evidence map›Paper›PMID 32945259›Full record

ArticleeLife2020

A novel DNA primase-helicase pair encoded by SCC

Aleksandra Bebel, Melissa A Walsh, Ignacio Mir-Sanchis, Phoebe A Rice

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Microbiology spectrum · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. How to survive pig farming: Mechanism of SCCFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aleksandra BebelDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.
Melissa A WalshDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.
Ignacio Mir-SanchisDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-6536-0045
Phoebe A RiceDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-3467-341X

Funding

Lifestyle of the SCCmec element and mechanisms of self-loading helicasesR01GM121655 · NIGMS · UNIVERSITY OF CHICAGO · PI RICE, PHOEBE A · 2017 to 2020
$1.7M
European Molecular Biology Organization ALTF 65-2017NIGMS NIH HHS R01 GM121655
6 · The paper itself

Abstract

Mobile genetic elements (MGEs) are a rich source of new enzymes, and conversely, understanding the activities of MGE-encoded proteins can elucidate MGE function. Here, we biochemically characterize three proteins encoded by a conserved operon carried by the Staphylococcal Cassette Chromosome (SCC

Indexed as

Amino Acid SequenceBacterial ProteinsDNA HelicasesDNA PrimaseMethicillin ResistanceSequence AlignmentStaphylococcus aureusBacterial ProteinsDNA HelicasesDNA PrimaseA-family polymerasebiochemistrychemical biologyhelicasemobile genetic elementsprimaseSCCmecStaphylococcus aureus

Identifiers

PMID32945259
PMCPMC7581432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.