ArticleActa paediatrica (Oslo, Norway : 1992)2021
Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age.
Article in Acta paediatrica (Oslo, Norway : 1992), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intelligence Quotient (IQ) in school-aged preterm infants: A systematic review.Frontiers in psychology · 2023Pooled it
- Ophthalmological outcomes, visual perception, fine motor precision, and visual-motor integration in children born very preterm.Developmental medicine and child neurology · 2026Article
- Cognition and language of 2-year-old very preterm children measured using brief validated parental report instruments: a cross-sectional study.European journal of pediatrics · 2026Article
- Predictors of language and reading outcomes in 12-year-old children born very preterm.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Do Bayley-III Composite Scores at 18-22 Months Corrected Age Predict Full-Scale IQ at 6-7 Years in Children Born Extremely Preterm?The Journal of pediatrics · 2023Article
- Bayley trajectories predict school readiness better than single assessments in formerly very preterm preschoolers.Pediatric research · 2023Article
- Neurodevelopmental outcomes of very low birth weight preterms in preschool childhood: a prospective cohort study.Italian journal of pediatrics · 2023Article
- Visual tracking at 4 months in preterm infants predicts 6.5-year cognition and attention.Pediatric research · 2022Article
- Article
- Neurodevelopmental disorders and somatic diagnoses in a national cohort of children born before 24 weeks of gestation.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the study was to investigate cognitive outcomes at 6.5 years in children born very preterm, in relation to neonatal characteristics and 2.5-year neurodevelopment.
methodsA prospective cohort, with gestational age 22.3-31.9 weeks, born 2004-2007, were examined at 2.5 years with the Bayley Scales of Infant and Toddler Development (Bayley-III) (n = 100) and at 6.5 years with the Wechsler Intelligence Scales (n = 91).
resultsNeonatal factors independently related to 6.5-year outcome were gestational age, retinopathy of prematurity and treated persistent ductus arteriosus. The Bayley-III cognitive scores explained only 44% of the Full-Scale Intelligence Quotient result at 6.5 years, and 22% of the children had Wechsler index results below -1 SD, indicating cognitive impairment, after average test results at 2.5 years. The relative risk to score below -1 SD on the Full-Scale IQ was 2.83 (95% CI 1.45-5.53) in children with gestational age below 28 weeks and 2.22 (95% CI 1.18-4.17) at gestational age 28-31 weeks.
conclusionVery preterm infants born in the 2000s had increased risks for impaired cognition at 6.5 years, but individual predictions based on neonatal risks and 2.5-year test results were not enough to identify all high-risk children.
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