Evidence map›Paper›PMID 32944809›Full record

ReviewAnalytical and bioanalytical chemistry2021

Review of analytical performance of COVID-19 detection methods.

Basant Giri, Shishir Pandey, Retina Shrestha, Krisha Pokharel, Frances S Ligler, Bhanu B Neupane

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed.

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  11. Two-Dimensional (2D) materials in the detection of SARS-CoV-2.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2023
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  16. Outcomes of hip fracture surgery during the COVID-19 pandemic.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
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  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Basant GiriCenter for Analytical Sciences, Kathmandu Institute of Applied Sciences, Kathmandu, 44600, Nepal.
Shishir PandeyCenter for Analytical Sciences, Kathmandu Institute of Applied Sciences, Kathmandu, 44600, Nepal.
Retina ShresthaCenter for Analytical Sciences, Kathmandu Institute of Applied Sciences, Kathmandu, 44600, Nepal.
Krisha PokharelCenter for Analytical Sciences, Kathmandu Institute of Applied Sciences, Kathmandu, 44600, Nepal.
Frances S LiglerJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA. fsligler@ncsu.edu.
Bhanu B NeupaneCenter for Analytical Sciences, Kathmandu Institute of Applied Sciences, Kathmandu, 44600, Nepal.

Funding

United States Agency for International Development AID-OAA-A-11-00012
6 · The paper itself

Abstract

In the recent SARS-CoV-2 pandemic, public health experts have emphasized testing, tracking infected people, and tracing their contacts as an effective strategy to reduce the spread of the virus. Several diagnostic methods are reported for detecting the coronavirus in clinical, research, and public health laboratories. Some tests detect the infection directly by detecting the viral RNA and other tests detect the infection indirectly by detecting the host antibodies. A diagnostic test during the pandemic should help make an appropriate clinical decision in a short period of time. Recently reported diagnostic methods for SARS-CoV-2 have varying throughput, batching capacity, requirement of infrastructure setting, analytical performance, and turnaround times ranging from a few minutes to several hours. These factors should be considered while selecting a reliable and rapid diagnostic method to help make an appropriate decision and prompt public health interventions. This paper reviews recent SARS-CoV-2 diagnostic methods published in journals and reports released by regulatory agencies. We compared the analytical efficiency including limit of detection, sensitivity, specificity, and throughput. In addition, we also looked into ease of use, affordability, and availability of accessories. Finally, we discuss the limitations of the methods and provide our perspectives on priorities for future test development.

Indexed as

Antibodies, ViralCOVID-19HumansPandemicsRNA, ViralSARS-CoV-2Sensitivity and SpecificityAntibodies, ViralRNA, ViralCoronavirusCOVID-19Disease diagnosisImmunoassaysRT-PCRSARS-CoV-2

Identifiers

PMID32944809
PMCPMC7498299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.