ArticleMolecular genetics and genomics : MGG2021
Comparative analysis of the pulmonary microbiome in healthy and diseased pigs.
Article in Molecular genetics and genomics : MGG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Profiling Fecal Microbiome and Metabolites in a Feline Infectious Peritonitis Virus Challenge Model in Kittens: A Pilot Discovery Study.International journal of molecular sciences · 2026Article
- Clinical and microbiota alterations in performance horses undergoing long-distance transport.Journal of veterinary internal medicine · 2026Article
- Disease-Group-Specific Antimicrobial Use Patterns and Farm-Level Stewardship Features in Large-Scale Hungarian Swine Herds: A Multi-Farm Survey.Animals : an open access journal from MDPI · 2026Article
- Exploring the functional microbiome of pigs within the porcine respiratory disease complex: viral-bacterial co-infections and virulence factor profiling.Microbiology spectrum · 2026Article
- Impact of whole-herd vaccination on a caprine coxiellosis outbreak: a longitudinal study ofFrontiers in microbiology · 2026Article
- Detection of infectious agents in lungs of slaughtered pigs in association with cranioventral pulmonary consolidation.Journal of veterinary research · 2025Article
- Challenges and Lessons Learned from a Field Trial on the Understanding of the Porcine Respiratory Disease Complex.Vaccines · 2025Article
- Nasal microbial diversity is associated with survival in piglets infected by a highly virulent PRRSV-1 strain.Animal microbiome · 2025Article
- Swine influenza-modified pulmonary microbiota.Frontiers in cellular and infection microbiology · 2025Article
- Lung microbiota of raccoon dogs (Frontiers in microbiology · 2025Article
- Article
- The developing pig respiratory microbiome harbors strains antagonistic to common respiratory pathogens.mSystems · 2024Article
- Metagenomic sequencing reveals swine lung microbial communities and metagenome-assembled genomes associated with lung lesions-a pilot study.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Article
- Article
- Influence of Mycoplasma hyopneumoniae natural infection on the respiratory microbiome diversity of finishing pigs.Veterinary research · 2022Article
- Review
- Analysis and Comparison of Gut Microbiome in Young Detection Dogs.Frontiers in microbiology · 2022Article
- Changes in the Nasal Microbiota of Pigs Following Single or Co-Infection with Porcine Reproductive and Respiratory Syndrome and Swine Influenza A Viruses.Pathogens (Basel, Switzerland) · 2021Article
- The porcine respiratory microbiome: recent insights and future challenges.Animal microbiome · 2021Review
- The Airway Pathobiome in Complex Respiratory Diseases: A Perspective in Domestic Animals.Frontiers in cellular and infection microbiology · 2021Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining attention. In order to study the relationship between lung microbiota and porcine respiratory disease complex (PRDC), the lung microbiota in healthy and diseased swine bronchoalveolar lavage fluids were analyzed and compared using the Illumina MiSeq sequencing platform. The predominant microbial communities of healthy and diseased swine were similar at the phylum level, mainly composed of Proteobacteria, Firmicutes, Tenericutes, and Bacteroidetes. However, the bacterial taxonomic communities of healthy and diseased swine differed at the genus level. The higher relative abundances of Lactococcus, Enterococcus, Staphylococcus, and Lactobacillus genera in healthy swine might provide more benefits for lung health, while the enhanced richness of Streptococcus, Haemophilus, Pasteurella, and Bordetella genera in diseased swine might be closely related to pathogen invasion and the occurrence of respiratory disease. In conclusion, the observed differences in the richness and diversity of lung microbiota can provide novel insights into their relationship with PRDC. Analyses of swine lung microbiota communities might produce an effective strategy for the control and prevention of respiratory tract infections.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.