Evidence map›Paper›PMID 32944212›Full record

ReviewTherapeutic advances in endocrinology and metabolism2020

Insulin-delivery methods for children and adolescents with type 1 diabetes.

Zavuga Zuberi, Elingarami Sauli, Liu Cun, Jing Deng, Wen-Jun Li, Xu-Liang He, Wen Li

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Zavuga ZuberiHunan Key Laboratory of Biological Nanomaterials and Devices, Hunan University of Technology, Hunan, PR China.
Elingarami SauliDepartment of Global Health and Biomedical Sciences, Nelson Mandela African Institution of Science and Technology, Arusha, United Republic of Tanzania.
Liu CunHunan Key Laboratory of Biological Nanomaterials and Devices, Hunan University of Technology, Hunan, PR China.
Jing DengHunan Key Laboratory of Biological Nanomaterials and Devices, Hunan University of Technology, Hunan, PR China.
Wen-Jun LiZhuzhou City People's Hospital, Affiliated Hospital of Changsha Medical College, Hunan, PR China.
Xu-Liang HeZhuzhou City People's Hospital, Affiliated Hospital of Changsha Medical College, Hunan, PR China.
Wen LiHunan Key Laboratory of Biological Nanomaterials and Devices, School of Life Sciences and Chemistry, Hunan University of Technology, Hunan, Zhuzhou 412007, PR China.ORCID https://orcid.org/0000-0002-6807-479X
Hunan University of Technology · CNNelson Mandela African Institution of Science and Technology · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efforts directed toward restoring normal metabolic levels by mimicking the physiological insulin secretion, thereby ensuring safety, efficacy, minimal invasiveness and conveniences, are of great significance in the management of type 1 diabetes among children and adolescents. Regardless of the various technologies being discovered in addressing invasiveness and enhancing medication adherence in the management of type 1 diabetes, yet limited success had been observed among children and adolescents. The multiple daily subcutaneous insulin injections route using vial and syringe, and occasionally insulin pens, remain the most predictable route for insulin administration among children and adolescents. However, this route has been associated with compromised patient compliance, fear of injections and unacceptability, resulting in poor glycemic control, which promote the demand for alternative routes of insulin administration. Alternative routes for delivering insulin are being investigated in children and adolescents with type 1 diabetes; these include the hybrid closed-loop 'artificial pancreas' system, oral, inhalation, intranasal routes, and others. This review article explores the current advances in insulin-delivery methods that address the needs of children and adolescents in the treatment of type 1 diabetes.

Indexed as

adolescentsartificial pancreaschildreninsulin deliverynasal insulintype 1 diabetes

Identifiers

PMID32944212
PMCPMC7466897
OpenAlexW3023104103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.