ArticleAudiology research2020
Sudden sensorineural hearing loss: What factors influence the response to therapy?
Article in Audiology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Optical coherence tomography angiography findings in patients with sudden sensorineural hearing loss.Scientific reports · 2025Article
- Early Detection of Hearing Impairment Signals Post-mRNA COVID-19 Vaccination: A Disproportionality Analysis Study on French Pharmacovigilance Database.Drug safety · 2025Article
- Profound Sensorineural Hearing Loss Following Typhoid Fever in a Young Adult Female: A Rare Complication.Case reports in infectious diseases · 2025Article
- The inflammatory and metabolic status of patients with sudden-onset sensorineural hearing loss.Frontiers in neurology · 2024Article
- Sudden sensorineural hearing loss: audiological profile during the COVID-19 pandemic.Frontiers in neurology · 2024Article
- Safety Signal Generation for Sudden Sensorineural Hearing Loss Following Messenger RNA COVID-19 Vaccination: Postmarketing Surveillance Using the French Pharmacovigilance Spontaneous Reporting Database.JMIR public health and surveillance · 2023Article
- Artificial Neural Network-Assisted Classification of Hearing Prognosis of Sudden Sensorineural Hearing Loss With Vertigo.IEEE journal of translational engineering in health and medicine · 2023Article
- [Association of sudden sensorineural hearing loss and its prognosis with the brain white matter hyperintensity].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022Article
- Sudden Sensorineural Hearing Loss in Mild COVID-19: Case Series and Analysis of the Literature.Audiology research · 2021Article
- Correlation between serum lipid and prognosis of idiopathic sudden sensorineural hearing loss: a prospective cohort study.Annals of translational medicine · 2021Article
- Hearing recovery prediction and prognostic factors of idiopathic sudden sensorineural hearing loss: a retrospective analysis with a deep neural network model.Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The standard treatment of Sudden Sensorineural Hearing Loss is based on oral steroids. In addition, intratympanic steroid is currently used in patients who fail to respond to oral treatment. The aim of the present study was to evaluate, in patients affected by SSHL, factors that influence the response to systemic and intratympanic steroid treatment. A retrospective analysis was conducted on 149 patients, all treated with systemic steroids. Moreover, patients not responsive to systemic therapy were treated with intratympanic steroids as salvage therapy. Auditory gain was assessed through the recovery rate at the discharge and after 30 days. Statistical analysis demonstrated that patients with delayed treatment and down-sloping auditory curve presented a poor recovery. Linear and stepwise regression showed that hypertriglyceridemia and hyperglycemia were negative prognostic factors. The prognosis of SSHL is affected by hyperglycemia and hypertriglyceridemia suggesting that a microvascular dysfunction within the cochlea could impair hearing recovery. Intratympanic steroid treatment was used as salvage treatment, however in patients with poor prognostic factors or at risk for side effects, it could be used in association with systemic treatment.
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