ArticleAnnals of general psychiatry2020
Untreated depressive symptoms significantly worsen quality of life in old age and may lead to the misdiagnosis of dementia: a cross-sectional study.
Article in Annals of general psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Case Definition for Diagnosed Alzheimer Disease and Related Dementias in Medicare.JAMA network open · 2024Pooled it
- Digital Cognitive Behavioral Therapy for Older Adults With Symptoms of Depression: Feasibility Cohort Study.JMIR formative research · 2026Article
- Optimizing antidepressant use in geriatric depression: expert consensus from French societies of geriatrics, old age psychiatry, and clinical pharmacy (SFGG, SF3PA, and SFPC).European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Association of Cognitive Impairment with Reduced Health-Related Quality of Life and Depression Among Survivors of Thrombotic Thrombocytopenic Purpura.Hematology reports · 2025Article
- Application of machine learning and temporal response function modeling of EEG data for differential diagnosis in primary progressive aphasia.Scientific reports · 2025Article
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- Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries.The Lancet. Global health · 2025Article
- Ipsa senectus morbus est? Approaching the unmet needs in geriatric depression: results from a national survey of medical experts.Frontiers in psychiatry · 2025Article
- Functional Cognitive Disorder: diagnostic challenges, clinical features, and future directions in a misunderstood condition.Frontiers in aging neuroscience · 2025Review
- Depression diagnosis from patient interviews using multimodal machine learning.Frontiers in psychiatry · 2025Article
- Public Health Challenges and Responses to the Growing Ageing Populations.Public health challenges · 2024Review
- Injurious Fall Risk Differences Among Older Adults With First-Line Depression Treatments.JAMA network open · 2024Article
- Coping strategies and adherence in people with mood disorder: a cross-sectional study.Frontiers in psychiatry · 2024Article
- Suicide in the Elderly - A Prevalent Phenomenon With Low Societal Awareness.International journal of public health · 2024Article
- Depression and Pseudodementia: Decoding the Intricate Bonds in an Italian Outpatient Setting.Brain sciences · 2023Article
- Evaluating the Modified Patient Health Questionnaire-2 and Insomnia Severity Index-2 for Daily Digital Screening of Depression and Insomnia: Validation Study.JMIR mental health · 2023Article
- Effectiveness of the Program to Encourage Active, Rewarding Lives (PEARLS) to reduce depression: a multi-state evaluation.Frontiers in public health · 2023Article
- Quality of life profiles and their associations with depressive symptoms and cognitive impairment of community-dwelling older adults in Hong Kong.Frontiers in public health · 2023Article
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Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies demonstrated the role of depressive mood and cognitive impairment in the background of elevated mortality and decreased Quality of Life (QoL) in old age. Our aim was to assess depressive and cognitive symptoms among older people in order to determine if those are recognized and treated or not, to elucidate the association between them and to investigate their impact on QoL.
methodsIn the framework of the ICT4Life project self-administered questionnaires and clinical screening tools were used to assess QoL, depressive symptoms and cognitive functions of 60 older persons over the age of 65.
resultsMales found to be depressed (53.8 vs. 40.4%) and cognitively declined (53.8 vs. 48.9%) more frequently; and had higher scores on the depression (6.85 vs. 5.32) and lower on the QoL (47.38 vs. 50.19) scales. Depressed older persons had lower cognitive levels (24.39 vs. 21.52) and their QoL was significantly poorer (53.97 vs. 43.85) than that of the non-depressed subjects. Depressive symptoms were detected in almost half of the older adults (43.9%), and the majority (80.77%) did not receive antidepressant medication.
conclusionsDepressive and cognitive symptoms found to be common among older people, but were not recognized and treated in most cases. Close correlation between depression and cognitive impairment was also confirmed, as well as the key role of depression in the background of pseudo-dementia and QoL decline. Early recognition of depressive symptoms is important not only to treat the underlying mood disorder, but also to improve QoL of older persons.
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