Evidence map›Paper›PMID 32943992›Full record

ReviewCancer cell international2020

Melatonin and urological cancers: a new therapeutic approach.

Mohammad Hossein Mehrzadi, Azam Hosseinzadeh, Kobra Bahrampour Juybari, Saeed Mehrzadi

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Empowering Melatonin Therapeutics withDiseases (Basel, Switzerland) · 2021
    Review
  10. Review
  11. ROR: Nuclear Receptor for Melatonin or Not?Molecules (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohammad Hossein MehrzadiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
Azam HosseinzadehRazi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Kobra Bahrampour JuybariDepartment of Pharmacology, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Saeed MehrzadiRazi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-6619-2330
Iran University of Medical Sciences · IRKashan University of Medical Sciences · IRSemnan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urological cancers are responsible for thousands of cancer-related deaths around the world. Despite all developments in therapeutic approaches for cancer therapy, the absence of efficient treatments is a critical and vital problematic issue for physicians and researchers. Furthermore, routine medical therapies contribute to several undesirable adverse events for patients, reducing life quality and survival time. Therefore, many attempts are needed to explore potent alternative or complementary treatments for great outcomes. Melatonin has multiple beneficial potential effects, including anticancer properties. Melatonin in combination with chemoradiation therapy or even alone could suppress urological cancers through affecting essential cellular pathways. This review discusses current evidence reporting the beneficial effect of melatonin in urological malignancies, including prostate cancer, bladder cancer, and renal cancer.

Indexed as

AngiogenesisApoptosisAutophagyBladder cancerChemotherapyInflammationMelatoninmetastasisOxidative stressProstate cancerRadiotherapyRenal cell carcinomaUrological cancers

Identifiers

PMID32943992
PMCPMC7488244
OpenAlexW3083852792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.