Evidence map›Paper›PMID 32943831›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2020

Clinical Experience in the Administration of Intravitreal Injection Therapy at a Tertiary University Hospital in Jordan During the COVID-19 Lockdown.

Omar A Saleh, Hisham Jammal, Noor Alqudah, Asem Alqudah, Nakhleh Abu-Yaghi

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Nonadherence to anti-VEGF intravitreal injections in patients with diabetic macular edema : The names of the authors.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  3. Article
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  9. Review
  10. Modifications of intravitreal injections in response to the COVID-19 pandemic.Journal of the Chinese Medical Association : JCMA · 2021
    Review
  11. Delayed follow-up of medical retina patients due to COVID-19: impact on disease activity and visual acuity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  12. Article
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  15. Diabetic Retinopathy Screening Adherence.Romanian journal of ophthalmology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Omar A SalehDepartment of Ophthalmology, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-4837-6042
Hisham JammalDepartment of Ophthalmology, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0002-1265-7224
Noor AlqudahDepartment of Ophthalmology, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0001-5341-9137
Asem AlqudahDepartment of Ophthalmology, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0002-8321-2572
Nakhleh Abu-YaghiDepartment of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.ORCID 0000-0002-6509-4082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the clinical experience with the delivery of intravitreal injection therapy to patients with various indications at a tertiary university hospital during the COVID-19 lockdown in Jordan.

methodsThis is a retrospective observational study of patients who received intravitreal injections between April 12th and May 9th, 2020, a period during the national COVID-19 lockdown (March 16th to June 6th, 2020). Special medical and logistic arrangements, priority and visual risk assessment and strict infection control precautions were implemented. Demographics, diagnosis, intravitreal injection history, medical history, ophthalmic examinations and optical coherence tomography data were collected and analyzed.

resultsIntravitreal injections were successfully administered to 132 patients with diabetic retinopathy, age-related macular degeneration and retinal vein occlusion. All logistic and transmission control measures were followed by the medical staff and patients with no incidents. No new exposures or COVID-19 positive cases were traced to our location or time of therapy. No complications related to the injections were recorded. The mean period of delay due to the lockdown from the original scheduled appointment was six weeks. Mean visual acuity significantly decreased from 20/55 before the lockdown to 20/70 after the lockdown, and mean central macular thickness significantly increased from 329 to 370 μ.

conclusionThe administration of intravitreal injection therapy during the COVID-19 lockdown under special safety precautions was feasible and successful. Resumption of the essential therapies and medical services during periods of pandemic restrictions while adhering to strict transmission control measures is encouraged.

Indexed as

age-related macular degenerationCOVID-19diabetic macular edemaintravitreal injectionslockdown

Identifiers

PMID32943831
PMCPMC7468368

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.