ArticleScientific reports2020
Causes and consequences of the opioid epidemic in the Netherlands: a population-based cohort study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Association of benzodiazepine and opioid use with hip fracture treated with arthroplasty: a nationwide case-control study.BMC geriatrics · 2026Article
- Changes in analgesic prescriptions in Dutch general practice.Scandinavian journal of primary health care · 2024Article
- Patients' perspectives about the role of primary healthcare providers in long-term opioid therapy: a qualitative study in Dutch primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024Article
- Patients' perspectives on tapering programmes for prescription opioid use disorder: a qualitative study.BMJ open · 2023Article
- The Imperative of Regulation: The Co-creation of a Medical and Non-medical US Opioid Crisis.Psychoactives · 2023Article
- Opioid sales and opioid-related poisonings in Switzerland: A descriptive population-based time-series analysis.The Lancet regional health. Europe · 2022Article
- Reducing opioid consumption levels post-operatively following gastrointestinal surgery - A systematic review of randomized trials.Surgery in practice and science · 2022Article
- Risk of drug-related upper gastrointestinal bleeding in the total population of the Netherlands: a time-trend analysis.BMJ open gastroenterology · 2022Article
- A Demographic and Regional Comparison of Opioid-Related Hospital Visits within Community Type in the United States.Journal of clinical medicine · 2021Article
- Preschool Language Development of Children Born to Women with an Opioid Use Disorder.Children (Basel, Switzerland) · 2021Article
- Comparison of Two Different Analgesic Prescription Strategies and Healthcare Systems: Slovenia vs. the Netherlands.Frontiers in pain research (Lausanne, Switzerland) · 2021Article
- Automated Classification of Whole Body Plethysmography Waveforms to Quantify Breathing Patterns.Frontiers in physiology · 2021Article
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12 authors.
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Abstract
Over the past decade opioid use has risen globally. The causes and consequences of this increase, especially in Europe, are poorly understood. We conducted a population-based cohort study using national statistics on analgesics prescriptions, opioid poisoning hospital admissions and deaths in the Netherlands from 2013 to 2017. Pain prevalence and severity was determined by using results of 2014-2017 Health Interview Surveys. Between 2013 and 2017 the proportion of residents receiving opioid prescription rose from 4.9% to 6.0%, and the proportion of those receiving NSAIDs decreased from 15.5% to 13.7%. Self-reported pain prevalence and severity remained constant, as 44.7% of 5,119 respondents reported no pain-impeded activities-of-daily-living in 2014 (aRR, 1.00 [95% CI, 0.95-1.06] in 2017 vs 2014). Over the observation period, the incidence of opioid poisoning hospitalization and death increased from 8.6 to 12.9 per 100,000 inhabitants. The incidence of severe outcomes related to opioid use increased, as 3.9% of 1,343 hospitalized for opioid poisoning died in 2013 and 4.6% of 2,055 in 2017. We demonstrated that NSAIDs prescription decreased and opioid prescription increased in the Netherlands since 2013, without an increase in pain prevalence and severity. Consequently, the incidence of severe outcomes related to opioids increased.
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