Evidence map›Paper›PMID 32943441›Full record

ArticleCancer research2020

CRISPR/Cas9-Mediated Point Mutation in

Cai Bowen, Maho Shibata, Hailan Zhang, Sarah K Bergren, Michael M Shen, Edward P Gelmann

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cai BowenDepartments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.
Maho ShibataDepartments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.ORCID 0000-0002-7056-3939
Hailan ZhangDivision of Hematology/Oncology, University of Arizona Medical Center, Tucson, Arizona.
Sarah K BergrenDepartments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.
Michael M ShenDepartments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.ORCID 0000-0002-4042-1657
Edward P GelmannDivision of Hematology/Oncology, University of Arizona Medical Center, Tucson, Arizona. gelmanne@arizona.edu.ORCID 0000-0003-1482-3334
Columbia University Irving Medical Center · USBanner - University Medical Center Tucson · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
Roles for Nkx3.1 in Prostate Cancer InitiationP01CA154293 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CORDON-CARDO, CARLOS · 2011 to 2015
$6.5M
Analysis of epithelial heterogeneity in prostate development and cancerR01CA238005 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEN, MICHAEL M. · 2019 to 2023
$2.1M
Investigation of luminal stem cells and castration resistance in prostate cancerK99CA194287 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIBATA, MAHO · 2015 to 2016
$226k
NCI NIH HHS K99 CA194287NCI NIH HHS P01 CA154293NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA238005
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsAnimalsGene EditingHomeodomain ProteinsMaleMiceMice, Inbred C57BLMice, Mutant StrainsPoint MutationProstatic NeoplasmsTranscription FactorsHomeodomain ProteinsNkx3-1 protein, mouseTranscription Factors

Identifiers

PMID32943441
PMCPMC7642110
OpenAlexW3087019890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.