ReviewAJNR. American journal of neuroradiology2020
The Perplexity Surrounding Chiari Malformations - Are We Any Wiser Now?
Review in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Redefining Chiari Malformation Type III: a systematic review of prognostic stratification based on a three-tier MRI-based anatomical classification.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Pooled it
- Deep Feature-Based Detection of Chiari Malformation Type I from Sagittal T2-Weighted MRI Using a Hybrid CNN-Machine Learning Framework.Diagnostics (Basel, Switzerland) · 2026Article
- Hidden Hollows of the Fetal Cranium-Lacunar Skull in Isolation.Case reports in obstetrics and gynecology · 2026Article
- Chiari 1 Malformation, Factors That May Influence Decision Making, and Introducing the Chiari 1 Malformation Severity Classification System.Journal of clinical medicine · 2025Article
- [Congenital brain malformations].Radiologie (Heidelberg, Germany) · 2024Article
- Geometric morphometric analysis of the brainstem and cerebellum in Chiari I malformation.Frontiers in neuroanatomy · 2024Article
- Acromegaly, Herniation of Cerebellar Tonsils, and Arnold-Chiari 1 Malformation: The Importance of Right Definitions.Case reports in endocrinology · 2024Article
- Research process, recap, and prediction of Chiari malformation based on bicentennial history of nomenclature and terms misuse.Neurosurgical review · 2023Review
- A C-Arm-Free Minimally Invasive Technique for Spinal Surgery: Cervical and Thoracic Spine.Medicina (Kaunas, Lithuania) · 2023Review
- The Pathogenesis of Chiari Malformation and Syringomyelia: A Case Report and Systematic Review of Current Theories.Cureus · 2023Article
- Onset of Chiari type 1 malformation: insights from a small series of intrauterine MR imaging cases.Neuroradiology · 2023Article
- Accurate Posterior Fossa Decompression Technique for Chiari Malformation Type I and a Syringomyelia With Navigation: A Technical Note.International journal of spine surgery · 2023Article
- Chiari Malformation Type 1 in Adults.Advances and technical standards in neurosurgery · 2023Article
- Chiari Type 1 Malformation and Syringomyelia in Children: Classification and Treatment Options.Advances and technical standards in neurosurgery · 2023Review
- Pediatric Chiari I malformation: novel and traditional measurements associated with syrinx and surgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Chiari Malformation (Update on Diagnosis and Treatment).Neurologic clinics · 2022Review
- New Association between Idiopathic Scoliosis and Luckenschadel Skull (Lacunar Skull).Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022Article
- Predictors of reoperation for spinal disorders in Chiari malformation patients with prior surgical decompression.Journal of craniovertebral junction & spineArticle
- Chiari III malformation with defect in Liliequist membrane on MR imaging.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chiari malformations are a diverse group of abnormalities of the brain, craniovertebral junction, and the spine. Chiari 0, I, and 1.5 malformations, likely a spectrum of the same malformation with increasing severity, are due to the inadequacy of the para-axial mesoderm, which leads to insufficient development of occipital somites. Chiari II malformation is possibly due to nonclosure of the caudal end of the neuropore, with similar pathogenesis in the rostral end, which causes a Chiari III malformation. There have been significant developments in the understanding of this complex entity owing to insights into the pathogenesis and advancements in imaging modalities and neurosurgical techniques. This article aims to review the different types and pathophysiology of the Chiari malformations, along with a description of the various associated abnormalities. We also highlight the role of ante- and postnatal imaging, with a focus on the newer techniques in the presurgical evaluation, with a brief mention of the surgical procedures and the associated postsurgical complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.