Evidence map›Paper›PMID 32943417›Full record

ArticleAJNR. American journal of neuroradiology2020

Antiplatelet Management for Stent-Assisted Coiling and Flow Diversion of Ruptured Intracranial Aneurysms: A DELPHI Consensus Statement.

J M Ospel, P Brouwer, F Dorn, A Arthur, M E Jensen, R Nogueira, R Chapot, F Albuquerque, C Majoie, M Jayaraman and 9 more

Erratum issuedOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. The safety profile of single antiplatelet therapy with flow diverters: Systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Perioperative Antiplatelet Therapy in the New Flow Diversion Era.Journal of neuroendovascular therapy · 2026
    Review
  11. Review
  12. Article
  13. Multicenter comparison of antiplatelet treatment strategies for urgent/emergent neuroendovascular stenting.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  14. Literature review and DELPHI consensus on follow-up and retreatment of intracranial aneurysms with intrasaccular devices.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  15. Article
  16. Review
  17. Flow diverter stent for the treatment of ruptured distal anterior cerebral artery: A retrospective multicenter analysis from CRETA registry.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  18. Y-stent-assisted coiling with pEGASUS stents for intracranial bifurcation aneurysms: A multi-center retrospective study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 18 institutions in 10 countries.

J M OspelDepartment of Clinical Neurosciences (J.M.O., M.G.), University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0029-6764
P BrouwerDepartment of Interventional Neuroradiology (P.B.), Karolinksa Hospital, Stockholm, Sweden.ORCID 0000-0003-0041-2833
F DornInstitute of Neuroradiology (F.D.), University of Bonn, Bonn, Germany.ORCID 0000-0001-9093-8307
A ArthurDepartment of Neurosurgery (A.A.), Semmes-Murphey Clinic/University of Tennessee, Memphis, Tennessee.ORCID 0000-0002-1536-1613
M E JensenDepartments of Neurological Surgery, Radiology, and Medical Imaging (M.E.J.), University of Virginia Health, Charlottesville, Virginia.ORCID 0000-0003-3000-7150
R NogueiraMarcus Stroke & Neuroscience Center (R.N.), Grady Health System, Atlanta, Georgia.ORCID 0000-0003-4532-153X
R ChapotDepartment of Neuroradiology (R.C.), Alfred Krupp Krankenhaus Essen, Essen, Germany.ORCID 0000-0002-2584-8361
F AlbuquerqueDepartment of Neurosurgery (F.A.), Barrow Neurological Institute, Phoenix, Arizona.ORCID 0000-0003-2655-3810
C MajoieDepartment of Radiology (C.M.), Academic Medical Center, Amsterdam, the Netherlands.ORCID 0000-0002-7600-9568
M JayaramanDepartments of Diagnostic Imaging, Neurology, and Neurosurgery (M.J.), Warren Alpert School of Medicine at Brown University, Providence, Rhode Island.ORCID 0000-0002-4588-5135
A TaylorGroote Schuur Hospital (A.T.), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-2692-2068
J LiuDepartment of Neurosurgery (J.L.), Changhai Hospital Naval Medical University, Shanghai, China.ORCID 0000-0003-2768-7298
J FiehlerDepartment of Diagnostic and Interventional Neuroradiology (J.F.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0001-8533-7478
N SakaiDepartment of Neurosurgery (N.S.), Kobe City Medical Center General Hospital, Kobe, Japan.ORCID 0000-0002-3289-1210
K OrlovMeshalkin National Medical Research Center (K.O.), Novosibirsk, Russian Federation.ORCID 0000-0002-4832-6689
D KallmesDepartment of Radiology (D.K.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-8495-0040
J F FraserDepartments of Neurosurgery, Neurology, Radiology, and Neuroscience (J.F.F.), University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-5980-3989
L ThibaultMember of the Scientific Committee of the World Federation of Interventional and Therapeutic Neuroradiology (L.T.).ORCID 0000-0001-9236-2356
M GoyalDepartment of Clinical Neurosciences (J.M.O., M.G.), University of Calgary, Calgary, Alberta, Canada mgoyal@ucalgary.ca.ORCID 0000-0001-9060-2109
University of Calgary · CAAlfried Krupp Hospital · DEAmsterdam UMC Location University of Amsterdam · NLBarrow Neurological Institute · USBrown University · USEmory University · USKarolinska University Hospital · SEKobe City Medical Center General Hospital · JPMayo Clinic · USMeshalkin National Medical Research Center · RUSecond Military Medical University · CNSemmes Murphey Foundation · USSociety of Interventional Radiology · USUniversität Hamburg · DEUniversity of Bonn · DEUniversity of Cape Town · ZAUniversity of Kentucky · USUniversity of Virginia Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThere is a paucity of data regarding antiplatelet management strategies in the setting of stent-assisted coiling/flow diversion for ruptured intracranial aneurysms. This study aimed to identify current challenges in antiplatelet management during stent-assisted coiling/flow diversion for ruptured intracranial aneurysms and to outline possible antiplatelet management strategies. MATERIALS AND

methodsThe modified DELPHI approach with an on-line questionnaire was sent in several iterations to an international, multidisciplinary panel of 15 neurointerventionalists. The first round consisted of open-ended questions, followed by closed-ended questions in the subsequent rounds. Responses were analyzed in an anonymous fashion and summarized in the final manuscript draft. The statement received endorsement from the World Federation of Interventional and Therapeutic Neuroradiology, the Japanese Society for Neuroendovascular Therapy, and the Chinese Neurosurgical Society.

resultsData were collected from December 9, 2019, to March 13, 2020. Panel members achieved consensus that platelet function testing may not be necessary and that antiplatelet management for stent-assisted coiling and flow diversion of ruptured intracranial aneurysms can follow the same principles. Preprocedural placement of a ventricular drain was thought to be beneficial in cases with a high risk of hydrocephalus. A periprocedural dual, intravenous, antiplatelet regimen with aspirin and a glycoprotein IIb/IIIa inhibitor was preferred as a standard approach. The panel agreed that intravenous medication can be converted to oral aspirin and an oral P2Y12 inhibitor within 24 hours after the procedure.

conclusionsMore and better data on antiplatelet management of patients with ruptured intracranial aneurysms undergoing stent-assisted coiling or flow diversion are urgently needed. Panel members in this DELPHI consensus study preferred a periprocedural dual-antiplatelet regimen with aspirin and a glycoprotein IIb/IIIa inhibitor.

Indexed as

Endovascular ProceduresAdultAneurysm, RupturedDelphi TechniqueEmbolization, TherapeuticFemaleHumansIntracranial AneurysmIntracranial ThrombosisMaleMiddle AgedPlatelet Aggregation InhibitorsRetrospective StudiesStentsPlatelet Aggregation Inhibitors

Identifiers

PMID32943417
PMCPMC7661082
OpenAlexW3087650872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.