Evidence map›Paper›PMID 32943003›Full record

ArticleBMC infectious diseases2020

First case report of Cryptococcus laurentii knee infection in a previously healthy patient.

Hetao Huang, Jianke Pan, Weiyi Yang, Jiongtong Lin, Yanhong Han, Kai Lan, Lingfeng Zeng, Guihong Liang, Jun Liu

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hetao HuangSecond School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jianke PanDepartment of Sports Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Weiyi YangDepartment of Sports Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Jiongtong LinSecond School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yanhong HanSecond School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Kai LanDepartment of Clinical Laboratory, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Lingfeng ZengDepartment of Sports Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Guihong LiangDepartment of Sports Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Jun LiuDepartment of Sports Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. liujun.gdtcm@hotmail.com.ORCID http://orcid.org/0000-0002-1943-3880
Guangzhou University of Chinese Medicine · CN

Funding

Excellent doctoral dissertation cultivation project of Guangzhou University of Chinese Medicine 20182102066National Ministry of Industry and the State Health Planning Commission"Orthopedic Surgery Robot Application Center"Construction Projects No: 2017MHDOSR1008National Natural Science Foundation of China No. 81873314Project of Guangdong Provincial Department of Finance No: [2014]157, [2018]8Science and Technology Research Project of Guangdong Provincial Hospital of Chinese Medicine No: YKYN2015M MS15
6 · The paper itself

Abstract

backgroundThe purpose of this case report was to report a case of Cryptococcus laurentii infection in the left knee of a previously healthy 29 year old male patient. CASE PRESENTATION: After an initial misdiagnosis and 7 months of failed treatment, the patient received nearly a month of treatment with voriconazole (200 mg IV q12 h) and knee irrigation with amphotericin B until the infection was controlled. The treatment continued with fluconazole for nearly 7 months and approximately 5 weeks of antibiotic treatment for a skin bacterial coinfection. In the end, the patient's symptoms disappeared completely, the left knee recovered well, and there was no recurrence of infection.

conclusionThe key points of successful treatment in this case were the thorough debridement, the adequate course of knee irrigation with antifungal drugs and more than 6 months of oral antifungal drugs that were able to eradicate the infection.

Indexed as

Administration, OralAdultAmphotericin BAntifungal AgentsArthritis, InfectiousCryptococcosisCryptococcusDebridementDiagnostic ErrorsFluconazoleFocal InfectionHumansKneeMaleSkin Diseases, BacterialVoriconazoleAmphotericin BAntifungal AgentsFluconazoleVoriconazoleCase reportCryptococcus laurentiiFungal infection

Identifiers

PMID32943003
PMCPMC7500548
OpenAlexW3087553385

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.