Evidence map›Paper›PMID 32942752›Full record

ArticleBiomedicines2020

ICP-Mass-Spectrometry Ionic Profile of Whole Saliva in Patients with Untreated and Treated Periodontitis.

Federica Romano, Alexandra Castiblanco, Francesca Spadotto, Federica Di Scipio, Mery Malandrino, Giovanni Nicolao Berta, Mario Aimetti

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In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federica RomanoDepartment of Surgical Sciences, Centro Interdipartimentale di Ricerca (C.I.R.), Dental School, Section of Periodontology, University of Turin, 10126 Turin, Italy.
Alexandra CastiblancoDepartment of Surgical Sciences, Centro Interdipartimentale di Ricerca (C.I.R.), Dental School, Section of Periodontology, University of Turin, 10126 Turin, Italy.
Francesca SpadottoDepartment of Surgical Sciences, Centro Interdipartimentale di Ricerca (C.I.R.), Dental School, Section of Periodontology, University of Turin, 10126 Turin, Italy.
Federica Di ScipioDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano (To) Turin, Italy.
Mery MalandrinoDepartment of Chemistry and Centre for Nanostructured Interfaces and Surfaces (NIS), University of Turin, 10125 Turin, Italy.ORCID 0000-0002-8352-0487
Giovanni Nicolao BertaDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano (To) Turin, Italy.ORCID 0000-0002-3263-9349
Mario AimettiDepartment of Surgical Sciences, Centro Interdipartimentale di Ricerca (C.I.R.), Dental School, Section of Periodontology, University of Turin, 10126 Turin, Italy.

Funding

Fondazione Cassa di Risparmio di Torino (CRT) n 2019.1012
6 · The paper itself

Abstract

Over the past decade, there has been growing interest in the association between macro and trace minerals in body fluids and systemic diseases related to chronic inflammation and oxidative stress. Due to the paucity of data in the literature on periodontitis, the aim of this cross-sectional study was to assess the relationship between mineral elements in saliva and periodontal status in patients with untreated and treated periodontitis compared to periodontally healthy controls. Salivary samples from 66 nonsmoker healthy patients (20 periodontally healthy, 24 untreated severe periodontitis and 22 treated severe periodontitis) were analyzed by using inductively coupled plasma mass-spectrometry (ICP-MS). Significant increases in copper (Cu), sodium (Na), iron (Fe) and manganese (Mn) concentrations occurred in saliva of severe periodontitis subjects compared to periodontally healthy controls. No differences were detected between healthy controls and treated periodontitis patients apart from levels of zinc (Zn) and lithium (Li) that were found to be increased and reduced, respectively, in periodontitis group. Most subjects were correctly separated by cluster analysis into active periodontitis and periodontally healthy individuals. Treated periodontitis individuals were classified as healthy subjects. Based on these preliminary results, the assessment of salivary concentration of mineral elements might be useful in discriminating periodontal health and disease.

Indexed as

inductively coupled plasma mass-spectrometrymetalsperiodontitissaliva

Identifiers

PMID32942752
PMCPMC7555328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.