Evidence map›Paper›PMID 32942640›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Berry Phenolic and Volatile Extracts Inhibit Pro-Inflammatory Cytokine Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB Signaling Pathway.

Inah Gu, Cindi Brownmiller, Nathan B Stebbins, Andy Mauromoustakos, Luke Howard, Sun-Ok Lee

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Anti-Inflammatory Effect of Extract fromJournal of microbiology and biotechnology · 2024
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  6. Review
  7. Article
  8. Article
  9. Pharmaceutics · 2024
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  16. Article
  17. Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Inah GuDepartment of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA.
Cindi BrownmillerDepartment of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA.
Nathan B StebbinsDepartment of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA.
Andy MauromoustakosAgricultural Statistics Laboratory, University of Arkansas, Fayetteville, AR 72701, USA.
Luke HowardDepartment of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA.
Sun-Ok LeeDepartment of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA.ORCID 0000-0002-4854-1346
University of Arkansas at Fayetteville · US

Funding

Arkansas Biosciences Institute .
6 · The paper itself

Abstract

Berries are a rich source of phytochemicals, especially phenolics well known for protective activity against many chronic diseases. Berries also contain a complex mixture of volatile compounds that are responsible for the unique aromas of berries. However, there is very limited information on the composition and potential health benefits of berry volatiles. In this study, we isolated phenolic and volatile fractions from six common berries and characterized them by HPLC/HPLC-MS and GC/GC-MS, respectively. Berry phenolic and volatile fractions were evaluated for an anti-inflammatory effect using lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells by measuring levels of pro-inflammatory cytokines and the nuclear factor-kappa B (NF-κB) signaling pathway. Results showed that LPS-induced excessive production of nitric oxide (NO), prostaglandin E

Indexed as

anti-inflammatory effectberry phenolicsberry volatilesinflammatory cytokinesnuclear factor-kappa B

Identifiers

PMID32942640
PMCPMC7554842
OpenAlexW3085747716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.