ArticleMolecules (Basel, Switzerland)2020
A New Method for In-Situ Skin Penetration Analysis by Confocal Raman Microscopy.
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- In Situ Raman Spectroscopy as a Valuable Tool for Monitoring Crystallization Kinetics in Molecular Glasses.Molecules (Basel, Switzerland) · 2024Article
- Progress in Topical and Transdermal Drug Delivery Research-Focus on Nanoformulations.Pharmaceutics · 2024Review
- Optical Methods for Non-Invasive Determination of Skin Penetration: Current Trends, Advances, Possibilities, Prospects, and Translation into In Vivo Human Studies.Pharmaceutics · 2023Review
- Novel aspects of Raman spectroscopy in skin research.Experimental dermatology · 2022Review
- FT-Raman Spectroscopy as a Tool to Study the Secondary Structures of Wheat Gliadin Proteins.Molecules (Basel, Switzerland) · 2021Article
- In-Line and Off-Line Monitoring of Skin Penetration Profiles Using Confocal Raman Spectroscopy.Pharmaceutics · 2021Article
- Evaluating In Vivo Penetration of Yeast Rice Ferment Filtrate Into Skin Using Confocal Raman Microspectroscopy: A Pilot Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In the development of dermal drug formulations and cosmetics, understanding the penetration properties of the active ingredients is crucial. Given that widespread methods, including tape stripping, lack in spatial resolution, while being time- and labour-intensive, Confocal Raman Microscopy is a promising alternative. In optimizing topically applied formulations, or the development of generic formulations, comparative in-situ measurements have a huge potential of saving time and resources. In this work, we show our approach to in-situ skin penetration analysis by confocal Raman Microscopy. To analyse feasibility of the approach, we used caffeine solutions as model vehicles and tested the effectiveness of 1,2-pentanediol as a penetration enhancer for delivery to the skin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.