Evidence map›Paper›PMID 32942548›Full record

ArticleInternational journal of molecular sciences2020

Dysregulation of Key Proteins Associated with Sperm Motility and Fertility Potential in Cancer Patients.

Manesh Kumar Panner Selvam, Renata Finelli, Saradha Baskaran, Ashok Agarwal

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. The Surface Proteome of Bovine Unsexed and Sexed Spermatozoa.Animals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Review
  6. Multigenerational Exposure to Uranium Changes Sperm Metabolome in Rats.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Manesh Kumar Panner SelvamAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.
Renata FinelliAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-5926-6407
Saradha BaskaranAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-4499-8680
Ashok AgarwalAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0003-0585-1026
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer has adverse effects on male reproductive health. Conventional semen analysis does not explain the molecular changes in the spermatozoa of cancer patients. Currently, proteomics is being widely used to identify the fertility-associated molecular pathways affected in spermatozoa. The objective of this study was to evaluate the sperm proteome of patients with various types of cancer. Cryopreserved semen samples from patients (testicular cancer,

Indexed as

Citric Acid CycleFertilityHumansMaleMitochondrial DiseasesNeoplasmsOxidative PhosphorylationPhenotypeProteomeProteomicsReproductionSemenSemen AnalysisSignal TransductionSirtuinsSpermatozoaProteomeSirtuinsbioinformaticscancermale infertilityproteomicssperm

Identifiers

PMID32942548
PMCPMC7554694
OpenAlexW3086669783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.