Evidence map›Paper›PMID 32941291›Full record

ArticleHealth physics2020

Lack of Cellular Inflammation in a Non-human Primate Model of Radiation Nephropathy.

Eric P Cohen, Ann M Farese, George A Parker, Maureen A Kane, Thomas J MacVittie

Open access · greenAbstract read
In one paragraph

Article in Health physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The NIAID/RNCP Biodosimetry Program: An Overview.Cytogenetic and genome research · 2023
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eric P CohenDepartments of Medicine, University of Maryland, School of Medicine, Baltimore, MD.
Ann M FareseRadiation Oncology, University of Maryland, School of Medicine, Baltimore, MD.
George A ParkerCharles River Laboratories, Durham, NC.
Maureen A KaneDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD.
Thomas J MacVittieRadiation Oncology, University of Maryland, School of Medicine, Baltimore, MD.
University of Maryland, Baltimore · USCharles River Laboratories (United States) · US

Funding

NIAID NIH HHS HHSN272201000046C
6 · The paper itself

Abstract

Inflammation is commonly cited as a mechanism of delayed effects of acute radiation exposure (DEARE). Confirmation of its presence could provide significant insight to targeted use of treatments or mitigators of DEARE. We sought to quantify the presence of cellular inflammation in kidneys of non-human primates that developed acute and chronic kidney injury after a partial body irradiation exposure. We show herein that cellular inflammation is not found as a component of either acute or chronic kidney injury. Other mechanistic pathways of injury must be sought.

Indexed as

Disease Models, AnimalAcute Radiation SyndromeAnimalsEnd Stage Liver DiseaseInflammationMacaca mulattaRadiation ExposureRadiation Injuries, Experimental

Identifiers

PMID32941291
PMCPMC8932376
OpenAlexW3087710851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.