Evidence map›Paper›PMID 32940995›Full record

ArticleAccounts of chemical research2020

Sulfono-γ-AApeptides as Helical Mimetics: Crystal Structures and Applications.

Peng Sang, Yan Shi, Bo Huang, Songyi Xue, Timothy Odom, Jianfeng Cai

Open access · greenAbstract read
In one paragraph

Article in Accounts of chemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 75 citations in OpenAlex.

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  18. Acta pharmaceutica Sinica. B · 2023
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  19. Sulfono-γ-AApeptides as Protein Helical Domain Mimetics to Manipulate the Angiogenesis.Chembiochem : a European journal of chemical biology · 2022
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Peng SangDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.
Yan ShiDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.
Bo HuangDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.
Songyi XueDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.
Timothy OdomDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.
Jianfeng CaiDepartment of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States.ORCID 0000-0003-3106-3306
University of South Florida · US

Funding

Recognition of Abeta monomeric helixR01AG056569 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI CHUANHAI CAO, Jianfeng Cai · 2017 to 2026
$4.1M
Antimicrobial agents derived from AApeptide biomaterialsR01AI152416 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CAI, JIANFENG · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI152416NIA NIH HHS R01 AG056569
6 · The paper itself

Abstract

Foldamers have defined and predictable structures, improved resistance to proteolytic degradation, enhanced chemical diversity, and are versatile in their mimicry of biological molecules, making them promising candidates in biomedical and material applications. However, as natural macromolecules exhibit endless folding structures and functions, the exploration of the applications of foldamers remains crucial. As such, it is imperative to continue to discover unnatural foldameric architectures with new frameworks and molecular scaffolds. To this end, we recently developed a new class of peptidomimetics termed ″γ-AApeptides", oligomers of γ-substituted-

Indexed as

PeptidomimeticsAmino Acid SequenceAnimalsBlood GlucoseCrystallography, X-RayGlucagon-Like Peptide 1Glucose Tolerance TestHydrogen BondingMiceMolecular ConformationPeptidesProtein BindingProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53Blood GlucoseGlucagon-Like Peptide 1PeptidesPeptidomimeticsProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53

Identifiers

PMID32940995
PMCPMC8903043
OpenAlexW3087366206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.