Evidence map›Paper›PMID 32940859›Full record

ArticleBiophysical reviews2020

From protein and its hydration water dynamics to controlling mechano-elasticity of cellular lipid membranes and cell migration via ionic liquids.

Antonio Benedetto

Open access · bronzeAbstract readLetter
In one paragraph

Article in Biophysical reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 3 countries.

Antonio BenedettoDepartment of Sciences, University of Roma Tre, 00146, Rome, Italy. antonio.benedetto@ucd.ie.ORCID https://orcid.org/0000-0002-9324-8595
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this invited Commentary, as requested, I will walk the reader through my research path starting from my first works on proteins and their hydration water dynamics to my most recent activity on the use of ionic liquids (ILs) as molecular handles to control and manipulate cell membrane mechano-elasticity and cell migration. In doing so I will comment on my research activity on polymers, proteins, natural bioprotectants, phospholipid bilayers, amyloids and cells, which I have carried out by combining several different experimental and computational approaches including neutron scattering, atomic force microscopy, classical molecular dynamics and ab initio calculations, used in tandem with several biological assays and a palette of complementary techniques ranging from calorimetry to static and dynamic light scattering. In parallel to this biophysical/chemical-physical core activity, a smaller portion of my interest and effort has been-I may say always-dedicated to the development of a new neutron scattering method/spectroscopy for dynamics based on "elastic" scattering. I will comment on this instrumental side of my research as well and show its relationship with the biophysical core of my activity. The overall picture that emerges is, from my personal prospective, of a coherent 13-year research path based on curiosity and a problem-solving approach, in which the fundamental importance of inter- and trans-disciplinary approaches and collaborations is emerging on the way, forecasting a prosper and intriguing future for physics in biology and in nanomedicine and bionanotechnology applications.

Indexed as

AmyloidogenesisAtomic force microscopyCell assaysCell membraneCell migrationComputer simulationsIonic liquidsLipid bilayersMembrane elasticityNeutron scatteringNeutron scattering instrumentationProtein dynamicsProtein hydration water dynamics

Identifiers

PMID32940859
PMCPMC7575653
OpenAlexW3087292210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.