Evidence map›Paper›PMID 32940841›Full record

ReviewInternational journal of legal medicine2020

Evaluation and review of ways to differentiate sources of ethanol in postmortem blood.

Zijie Lin, Hao Wang, Alan Wayne Jones, Fanglin Wang, Yunfeng Zhang, Yulan Rao

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In one paragraph

Review in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  3. Efficacy ofFoods (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Zijie LinDepartment of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, People's Republic of China.
Hao WangDepartment of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, People's Republic of China.
Alan Wayne JonesDivision of Drug Research, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Fanglin WangInstitute of Forensic Science, Ministry of Public Security, Beijing, 100038, People's Republic of China.
Yunfeng ZhangInstitute of Forensic Science, Ministry of Public Security, Beijing, 100038, People's Republic of China.
Yulan RaoDepartment of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, People's Republic of China. yl_rao@163.com.ORCID http://orcid.org/0000-0002-5728-7888
Fudan University · CNMinistry of Public Security of the People's Republic of China · CNLinköping University · SEShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate determination of a person's blood alcohol concentration (BAC) is an important task in forensic toxicology laboratories because of the existence of statutory limits for driving a motor vehicle and workplace alcohol testing regulations. However, making a correct interpretation of the BAC determined in postmortem (PM) specimens is complicated, owing to the possibility that ethanol was produced in the body after death by the action of various micro-organisms (e.g., Candida species) and fermentation processes. This article reviews various ways to establish the source of ethanol in PM blood, including collection and analysis of alternative specimens (e.g., bile, vitreous humor (VH), and bladder urine), the identification of non-oxidative metabolites of ethanol, ethyl glucuronide (EtG) and ethyl sulfate (EtS), the urinary metabolites of serotonin (5-HTOL/5-HIAA), and identification of n-propanol and n-butanol in blood, which are known putrefaction products. Practical utility of the various biomarkers including specificity and stability is discussed.

Indexed as

Blood Alcohol Content1-Butanol1-PropanolAutopsyEthanolFlame IonizationForensic ToxicologyGas Chromatography-Mass SpectrometryGlucuronatesSerotoninSpecimen HandlingSulfuric Acid Esters1-Butanol1-PropanolBlood Alcohol Contentdiethyl sulfateEthanolethyl glucuronideGlucuronatesSerotoninSulfuric Acid EstersAlternative specimensBiomarkersEthanol analysisInterpretationPostmortem synthesis

Identifiers

PMID32940841
OpenAlexW3085264056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.