ArticleIntensive care medicine experimental2020
Diagnostic characteristics of 11 formulae for calculating corrected flow time as measured by a wearable Doppler patch.
Article in Intensive care medicine experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume responsiveness in general anesthesia patients: a prospective, observational study.Journal of clinical monitoring and computing · 2026Observational
- Correlation between carotid Doppler ultrasound-derived parameters and cardiac output measurements: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2025Article
- A framework for flow time measured by Doppler ultrasound.The ultrasound journal · 2025Article
- Evaluation of hemorrhagic shock and fluid resuscitation in pigs using handless Doppler carotid artery ultrasound.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Simultaneous Venous-Arterial Doppler Ultrasound During Early Fluid Resuscitation to Characterize a Novel Doppler Starling Curve: A Prospective Observational Pilot Study.Journal of intensive care medicine · 2024Observational
- Inferior Vena Caval Measures Do Not Correlate with Carotid Artery Corrected Flow Time Change Measured Using a Wireless Doppler Patch in Healthy Volunteers.Diagnostics (Basel, Switzerland) · 2023Article
- Simultaneous venous-arterial Doppler during preload augmentation: illustrating the Doppler Starling curve.The ultrasound journal · 2023Article
- A Novel Spectral Index for Tracking Preload Change from a Wireless, Wearable Doppler Ultrasound.Diagnostics (Basel, Switzerland) · 2023Article
- The effect of gravity-induced preload change on the venous excess ultrasound (VExUS) score and internal jugular vein Doppler in healthy volunteers.Intensive care medicine experimental · 2023Article
- Evaluating corrected carotid flow time as a non-invasive parameter for trending cardiac output and stroke volume in cardiac surgery patients.Journal of ultrasound · 2023Observational
- The time cost of physiologically ineffective intravenous fluids in the emergency department: an observational pilot study employing wearable Doppler ultrasound.Journal of intensive care · 2023Article
- Carotid artery velocity time integral and corrected flow time measured by a wearable Doppler ultrasound detect stroke volume rise from simulated hemorrhage to transfusion.BMC research notes · 2022Article
- Temporal concordance between pulse contour analysis, bioreactance and carotid doppler during rapid preload changes.PloS one · 2022Article
- Article
- The Doppler shock index measured by a wearable ultrasound patch accurately detects moderate-to-severe central hypovolemia during lower body negative pressure.Journal of the American College of Emergency Physicians open · 2021Article
- Ability of Carotid Corrected Flow Time to Predict Fluid Responsiveness in Patients Mechanically Ventilated Using Low Tidal Volume after Surgery.Journal of clinical medicine · 2021Article
- Carotid Doppler Measurement Variability in Functional Hemodynamic Monitoring: An Analysis of 17,822 Cardiac Cycles.Critical care explorations · 2021Article
- A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery.Scientific reports · 2021Article
- Inferring the Frank-Starling Curve From Simultaneous Venous and Arterial Doppler: Measurements From a Wireless, Wearable Ultrasound Patch.Frontiers in medical technology · 2021Article
- The Correlation between Carotid Artery Corrected Flow Time and Velocity Time Integral during Central Blood Volume Loss and Resuscitation.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChange of the corrected flow time (Ftc) is a surrogate for tracking stroke volume (SV) in the intensive care unit. Multiple Ftc equations have been proposed; many have not had their diagnostic characteristics for detecting SV change reported. Further, little is known about the inherent Ftc variability induced by the respiratory cycle. MATERIALS AND
methodsUsing a wearable Doppler ultrasound patch, we studied the clinical performance of 11 Ftc equations to detect a 10% change in SV measured by non-invasive pulse contour analysis; 26 healthy volunteers performed a standardized cardiac preload modifying maneuver.
resultsOne hundred changes in cardiac preload and 3890 carotid beats were analyzed. Most of the 11 Ftc equations studied had similar diagnostic attributes. Wodeys' and Chambers' formulae had identical results; a 2% change in Ftc detected a 10% change in SV with a sensitivity and specificity of 96% and 93%, respectively. Similarly, a 3% change in Ftc calculated by Bazett's formula displayed a sensitivity and specificity of 91% and 93%. Ftc
conclusionsMost of the 11 different equations used to calculate carotid artery Ftc from a wearable Doppler ultrasound patch had similar thresholds and abilities to detect SV change in healthy volunteers. Variation in Ftc induced by the respiratory cycle is important; measuring a clinically significant change in Ftc with statistical confidence requires a large sample of beats.
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