Evidence map›Paper›PMID 32940685›Full record

ReviewBiochemical Society transactions2020

Review on material parameters to enhance bone cell function in vitro and in vivo.

Eric Madsen, Merjem Mededovic, David H Kohn

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eric MadsenDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, Michigan, U.S.A.
Merjem MededovicDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, U.S.A.
David H KohnDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, Michigan, U.S.A.
University of Michigan · US

Funding

Engineering anti-fragile tooth/restorative interfacesR01DE026116 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOHN, DAVID H. · 2016 to 2020
$1.4M
Functionalization of biomimetic apatite with mineral binding peptides for bone tissue engineeringF30DE028465 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MADSEN, ERIC J · 2018 to 2023
$226k
NIDCR NIH HHS F30 DE028465NIDCR NIH HHS R01 DE026116
6 · The paper itself

Abstract

Bone plays critical roles in support, protection, movement, and metabolism. Although bone has an innate capacity for regeneration, this capacity is limited, and many bone injuries and diseases require intervention. Biomaterials are a critical component of many treatments to restore bone function and include non-resorbable implants to augment bone and resorbable materials to guide regeneration. Biomaterials can vary considerably in their biocompatibility and bioactivity, which are functions of specific material parameters. The success of biomaterials in bone augmentation and regeneration is based on their effects on the function of bone cells. Such functions include adhesion, migration, inflammation, proliferation, communication, differentiation, resorption, and vascularization. This review will focus on how different material parameters can enhance bone cell function both in vitro and in vivo.

Indexed as

RegenerationAdsorptionAnimalsBiocompatible MaterialsBone and BonesBone ResorptionCell AdhesionCell CommunicationCell DifferentiationCell MovementCell ProliferationHumansInflammationIn Vitro TechniquesMaterials TestingOsteocytesBiocompatible Materialsbiocompatibilitybiomaterialsbonecell functionsmaterial parametersosseointegration

Identifiers

PMID32940685
PMCPMC7606666
OpenAlexW3087249442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.