Evidence map›Paper›PMID 32940195›Full record

ArticlePsychological medicine2022

The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study.

Georgina Krebs, Lorena Fernández de la Cruz, Frühling V Rijsdijk, Daniel Rautio, Jesper Enander, Christian Rück, Paul Lichtenstein, Sebastian Lundström, Henrik Larsson, Thalia C Eley and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

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  6. Body dysmorphic disorder.Nature reviews. Disease primers · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Georgina KrebsKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.ORCID 0000-0002-5353-5645
Lorena Fernández de la CruzDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.ORCID 0000-0002-1571-5485
Frühling V RijsdijkKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.ORCID 0000-0003-4762-2803
Daniel RautioDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
Jesper EnanderDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.ORCID 0000-0002-1897-5549
Christian RückDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.ORCID 0000-0002-8742-0168
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Sebastian LundströmGillberg Neuropsychiatry Centre, Centre for Ethics, Law and Mental Healt, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-7235-8499
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-6851-3297
Thalia C EleyKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.ORCID 0000-0001-6458-0700
David Mataix-ColsDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.ORCID 0000-0002-4545-0924
Stockholm County Council · SEKing's College London · GBKarolinska Institutet · SEÖrebro University · SEUniversity of Gothenburg · SE

Funding

Department of HealthMedical Research Council MR/M021475/1Medical Research Council MR/N001400/1
6 · The paper itself

Abstract

backgroundPrevious research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focussed on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the relationship remains unknown.

methodsTwo independent twin samples were identified through the Child and Adolescent Twin Study in Sweden, at ages 18 (N = 6027) and 24 (N = 3454). Participants completed a self-report measure of BDD symptom severity. Young people and parents completed items assessing suicidal ideation/behaviours. Logistic regression models tested the association of suicidality outcomes with: (a) probable BDD, classified using an empirically derived cut-off; and (b) continuous scores of BDD symptoms. Bivariate genetic models examined the aetiology of the association between BDD symptoms and suicidality at both ages.

resultsSuicidal ideation and behaviours were common among those with probable BDD at both ages. BDD symptoms, measured continuously, were linked with all aspects of suicidality, and associations generally remained significant after adjusting for depressive and anxiety symptoms. Genetic factors accounted for most of the covariance between BDD symptoms and suicidality (72.9 and 77.7% at ages 18 and 24, respectively), but with significant non-shared environmental influences (27.1 and 22.3% at ages 18 and 24, respectively).

conclusionsBDD symptoms are associated with a substantial risk of suicidal ideation and behaviours in late adolescence and early adulthood. This relationship is largely explained by common genetic liability, but non-shared environmental effects are also significant and could provide opportunities for prevention among those at high-risk.

Indexed as

Body Dysmorphic DisordersSuicideAdolescentChildHumansRisk FactorsSelf ReportSuicidal IdeationSwedenYoung Adultadolescencebody dysmorphic disordergeneticssuicidal ideationsuicide attemptstwin design

Identifiers

PMID32940195
PMCPMC9157307
OpenAlexW3087574958

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.