Evidence map›Paper›PMID 32940146›Full record

ArticleTissue engineering. Part A2021

Degradation-Dependent Protein Release from Enzyme Sensitive Injectable Glycol Chitosan Hydrogel.

Shalini V Gohil, Aiswaria Padmanabhan, Ho-Man Kan, Manakamana Khanal, Lakshmi S Nair

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shalini V GohilDepartment of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA.
Aiswaria PadmanabhanDepartment of Materials Science and Engineering, University of Connecticut, Storrs, Connecticut, USA.
Ho-Man KanDepartment of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA.
Manakamana KhanalDepartment of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA.
Lakshmi S NairDepartment of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA.

Funding

Novel injectable analgesic delivery system for musculoskeletal pain managementR01AR075143 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI NAIR, LAKSHMI S · 2019 to 2023
$2.1M
NIAMS NIH HHS R01 AR075143
6 · The paper itself

Abstract

Glycol chitosan (GC) is a hydrophilic chitosan derivative, known for its aqueous solubility. Previously, we have demonstrated the feasibility of preparing injectable, enzymatically crosslinked hydrogels from HPP [3-(4-Hydroxyphenyl)-propionic acid (98%)]-modified GC. However, HPP-GC gels showed very slow degradation, which presents challenges as an

Indexed as

ChitosanHydrogelsAnimalsPolymersRheologyChitosanglycol-chitosanHydrogelsPolymerschitosandegradationhydrogelprotein releasesubcutaneous implantation

Identifiers

PMID32940146
PMCPMC8336245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.