Evidence map›Paper›PMID 32940049›Full record

ArticleCartilage2021

Smoking Is Associated with Anterior Ankle Impingement After Isolated Autologous Matrix-Induced Chondrogenesis for Osteochondral Lesions of the Talus.

Arnd F Viehöfer, Fabio Casari, Felix W A Waibel, Silvan Beeler, Florian B Imhoff, Stephan H Wirth, Jakob Ackermann

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Arnd F ViehöferDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Fabio CasariDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Felix W A WaibelDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-3991-8743
Silvan BeelerDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Florian B ImhoffDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Stephan H WirthDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.
Jakob AckermannDepartment of Orthopedics, University Hospital Balgrist, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4063-5815
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine potential predictive associations between patient-/lesion-specific factors, clinical outcome and anterior ankle impingement in patients that underwent isolated autologous matrix-induced chondrogenesis (AMIC) for an osteochondral lesion of the talus (OLT).

designThirty-five patients with a mean age of 34.7 ± 15 years who underwent isolated cartilage repair with AMIC for OLTs were evaluated at a mean follow-up of 4.5 ± 1.9 years. Patients completed AOFAS (American Orthopaedic Foot and Ankle Society) scores at final follow-up, as well as Tegner scores at final follow-up and retrospectively for preinjury and presurgery time points. Pearson correlation and multivariate regression models were used to distinguish associations between patient-/lesion-specific factors, the need for subsequent surgery due to anterior ankle impingement and patient-reported outcomes.

resultsAt final follow-up, AOFAS and Tegner scores averaged 92.6 ± 8.3 and 5.1 ± 1.8, respectively. Both body mass index (BMI) and duration of symptoms were independent predictors for postoperative AOFAS and Δ preinjury to postsurgery Tegner with positive smoking status showing a trend toward worse AOFAS scores, but this did not reach statistical significance (

conclusionIn particular, patients with normal BMI and chronic symptoms benefit from AMIC for the treatment of OLTs. Conversely, smoking cessation should be considered before AMIC due to the increased risk of subsequent surgery and possibly worse clinical outcome seen in active smokers.

Indexed as

ChondrogenesisAdultAnkleAutograftsFemaleHumansIntra-Articular FracturesMaleMiddle AgedOsteoarthritisRetrospective StudiesSmokingTalusTransplantation, AutologousYoung Adultankleautologous matrix-induced chondrogenesiscartilage lesioncartilage repairosteoarthritissmokingtalus

Identifiers

PMID32940049
PMCPMC8808944
OpenAlexW3087544587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.