Evidence map›Paper›PMID 32939623›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020

Endoscopic Submucosal Dissection for Upper Gastrointestinal Neoplasia-a North American Perspective.

Alex Chen, Michael Chen, Maude Trepanier, Aya Siblini, Carmen Mueller, Jonathan Cools-Lartigue, Jonathan Spicer, Lorenzo Ferri

Abstract read
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In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alex ChenDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Michael ChenDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Maude TrepanierDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Aya SibliniDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Carmen MuellerDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Jonathan Cools-LartigueDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Jonathan SpicerDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada.
Lorenzo FerriDepartment of Surgery, Division of Thoracic Surgery, Montreal General Hospital, McGill University Health Centre, Room L8-505, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada. lorenzo.ferri@mcgill.ca.
Montreal General Hospital · CAMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOrgan-sparing endoscopic submucosal dissection (ESD) is an acceptable treatment strategy for superficial neoplastic lesions of the esophagus and stomach. The adoption of this technique has lagged in North America compared with Asia, and we sought to report on our experiences with ESD for upper GI neoplasia.

methodsA prospectively entered database of all patients undergoing endoscopic resection of esophageal and gastric neoplasia at McGill University from 2009 to 2019 was queried for those who received ESD.

resultsA total of 103 consecutive ESDs were identified from 2009 to 2019. Seventy-one (69%) patients were male and the median age was 72 (range: 38-90). Sixty-one (59%) cases were esophageal and 42 (41%) gastric. Forty-nine (48%) were performed in the endoscopy suite under local sedation only. Perforation occurred in 9 patients (7 esophageal and 2 stomach), of which 3 required operative repair. Histology was principally invasive carcinoma (79, 77%), with 17 (16%) dysplastic lesions (e.g., HGD), 1 (1%) neuroendocrine tumor, and 7 (7%) benign lesions. En bloc resection was achieved in 90 (87%), and the complete resection rate was 74 (72%), with 51 (50%) of procedures fulfilling the criteria for curative resection. At medium of 23-month (2-199) follow-up of these 51 curative resections, one case of recurrent carcinoma was found at follow-up and was managed with repeat endoscopic resection. Non-curative ESDs were found 45 (R1 resection = 29: risk of lymph node metastasis = 16), 21 had active surveillance, and 24 were resected.

conclusionESD is a viable, effective, and safe therapeutic and staging modality for superficial lesions of the stomach and esophagus.

Indexed as

Endoscopic Mucosal ResectionEsophageal NeoplasmsAgedAsiaFemaleHumansMaleNeoplasm Recurrence, LocalTreatment OutcomeUnited StatesEndoscopic submucosal dissectionEsophageal neoplasmGastric neoplasm

Identifiers

PMID32939623
OpenAlexW3085177268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.