Evidence map›Paper›PMID 32939592›Full record

ArticleBreast cancer research and treatment2021

Oncotype DX testing in node-positive breast cancer strongly impacts chemotherapy use at a comprehensive cancer center.

Katya Losk, Rachel A Freedman, Alison Laws, Olga Kantor, Elizabeth A Mittendorf, Zhenying Tan-Wasielewski, Lorenzo Trippa, Nancy U Lin, Eric P Winer, Tari A King

Abstract read
PubMed Publisher
In one paragraph

Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Real-World Implications of the SOUND Trial.Annals of surgical oncology · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Katya LoskDepartment of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA. katya_losk@dfci.harvard.edu.ORCID http://orcid.org/0000-0002-5171-2994
Rachel A FreedmanDepartment of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA.
Alison LawsDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Olga KantorDivision of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Elizabeth A MittendorfBreast Oncology Program, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Zhenying Tan-WasielewskiDepartment of Biostatistics, Dana-Farber Cancer Institute, Boston, MA, USA.
Lorenzo TrippaDepartment of Biostatistics, Dana-Farber Cancer Institute, Boston, MA, USA.
Nancy U LinDepartment of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA.
Eric P WinerDepartment of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA.
Tari A KingBreast Oncology Program, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Brigham and Women's Hospital · USDana-Farber Cancer Institute · USHarvard University · US

Funding

Individualizing surveillance mammography for older breast cancer survivorsR21CA227615 · NCI · DANA-FARBER CANCER INST · PI FREEDMAN, RACHEL ANN · 2019 to 2020
$422k
American Cancer Society 125912-MRSG-14-240-01-CPPBNCI NIH HHS R21CA227615-01A1Susan G. Komen CCRCR18552788
6 · The paper itself

Abstract

purposeIn 2016, we initiated standardized "reflex" Oncotype DX Recurrence Score (RS) testing for patients ≤ 65 years with pT1-2N0-1 HR

methodsPatients with stage I-III HR

resultsWe identified 347 HR

conclusionMost RS-tested HR

Indexed as

Breast NeoplasmsChemotherapy, AdjuvantFemaleGene Expression ProfilingHumansNeoplasm Recurrence, LocalReceptors, EstrogenRiskReceptors, EstrogenAdjuvant chemotherapyLymph node-positive breast cancerOncotype DX recurrence score

Identifiers

PMID32939592
OpenAlexW3085295356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.