Evidence map›Paper›PMID 32939442›Full record

ArticleAnnals of eye science2020

Focal alteration of the intraretinal layers in neurodegenerative disorders.

Shriya Airen, Ce Shi, Zhiping Liu, Bonnie E Levin, Joseph F Signorile, Jianhua Wang, Hong Jiang

Abstract read
In one paragraph

Article in Annals of eye science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shriya AirenMiller School of Medicine, University of Miami, Miami, FL, USA.
Ce ShiDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Zhiping LiuDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Bonnie E LevinDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Joseph F SignorileDepartment of Kinesiology and Sports Sciences, University of Miami, FL, USA.
Jianhua WangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Hong JiangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
Novel Biomarkers of Small Vessel Contributions to Vascular Cognitive Impairment and Dementia (VCID)R01NS111115 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A, WANG, JIANHUA · 2019 to 2023
$3.7M
NEI NIH HHS P30 EY014801NINDS NIH HHS R01 NS111115
6 · The paper itself

Abstract

Focal intraretinal alterations have been studied to advance our understanding of the pathology of neurodegenerative diseases. The current literature involving focal alterations in the intraretinal layers was reviewed through PubMed using the search terms "focal alteration", "region of interest", "optical coherence tomography", "glaucoma", "multiple sclerosis", "Alzheimer's disease", "Parkinson disease", "neurodegenerative diseases" and other related items. It was found that focal alterations of intraretinal layers were different in various neurodegenerative diseases. The typical focal thinning might help differentiate various ocular and cerebral diseases, track disease progression, and evaluate the outcome of clinical trials. Advanced exploration of focal intraretinal alterations will help to further validate their clinical and research utility.

Indexed as

cerebral disorderfocal alterationocular diseaseOptical coherence tomography (OCT)

Identifiers

PMID32939442
PMCPMC7491919

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.