Evidence map›Paper›PMID 32939358›Full record

ArticleOpen forum infectious diseases2020

Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis.

Gemechu Churiso, Saskia van Henten, Lieselotte Cnops, Julia Pollmann, Roma Melkamu, Mulualem Lemma, Amare Kiflie, Helina Fikre, Johan van Griensven, Wim Adriaensen

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. A Journey on the Skin Microbiome: Pitfalls and Opportunities.International journal of molecular sciences · 2021
    Review
  8. AssessingFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gemechu ChurisoDepartment of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
Saskia van HentenUnit of Neglected Tropical Diseases, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-6627-0474
Lieselotte CnopsUnit of Neglected Tropical Diseases, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0003-0658-1291
Julia PollmannUnit of Neglected Tropical Diseases, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Roma MelkamuLeishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
Mulualem LemmaDepartment of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
Amare KiflieDepartment of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
Helina FikreLeishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
Johan van GriensvenUnit of Neglected Tropical Diseases, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-6581-2964
Wim AdriaensenUnit of Neglected Tropical Diseases, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.

Indexed as

cutaneous leishmaniasisdiagnosisLeishmania aethiopicasample collection

Identifiers

PMID32939358
PMCPMC7486950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.