Evidence map›Paper›PMID 32939325›Full record

ArticleOncoimmunology2020

Human innate immune cell crosstalk induces melanoma cell senescence.

Felix Funck, Jens Pahl, Lenka Kyjacova, Lukas Freund, Stephanie Oehrl, Galina Gräbe, Silvia Pezer, Jessica C Hassel, Jonathan Sleeman, Adelheid Cerwenka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Heterogeneity of monocytes in cancer.American journal of cancer research · 2025
    Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Felix FunckDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Jens PahlDepartment for Immunobiochemistry, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Lenka KyjacovaEuropean Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Lukas FreundDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Stephanie OehrlDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Galina GräbeDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Silvia PezerDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Jessica C HasselDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Jonathan SleemanEuropean Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Adelheid CerwenkaDepartment for Immunobiochemistry, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Knut SchäkelDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DERoche (United States) · USUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mononuclear phagocytes and NK cells constitute the first line of innate immune defense. How these cells interact and join forces against cancer is incompletely understood. Here, we observed an early accumulation of slan

Indexed as

Killer Cells, NaturalMelanomaCellular SenescenceHumansImmunity, InnateMonocytesTumor MicroenvironmentcytokinesmelanomaNK cellsenescenceslanMo

Identifiers

PMID32939325
PMCPMC7470184
OpenAlexW3082516543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.