ArticleNature communications2020
Ultralong purely organic aqueous phosphorescence supramolecular polymer for targeted tumor cell imaging.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 289 citations in OpenAlex.
- Ultrastrong Host-Guest Recognition Driven Chiral Supramolecular Polymers with Circularly Polarized Luminescence in Water.Polymers · 2026Article
- Recent Advances of Organic Room Temperature Phosphorescence for Biological Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Reversible Stress-memory Phosphorescent Carbon Nanodots via Supramolecular Confinement Engineering for Aerospace Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Organic room temperature phosphorescence co-crystal with reversible acid/base stimulus response.Smart molecules : open access · 2025Article
- Intermolecular charge transfer as an excited-state modulator for dual delayed luminescence in doping systems.Nature communications · 2025Article
- Building bridges through dynamic coupling for organic phosphorescence.Nature communications · 2025Article
- Bio-Based Thermoplastic Room Temperature Phosphorescent Materials with Closed-Loop Recyclability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Solvent-free processing of lignin into robust room temperature phosphorescent materials.Nature communications · 2025Article
- Enabling Aqueous Phase Long-lived Deep-blue Phosphorescence With Layered Double Hydroxide.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Luminescence Properties of Hoechst 33258 in Polyvinyl Alcohol Films.International journal of molecular sciences · 2025Article
- Regulating Triplet Excitons of Organic Luminophores for Promoted Bioimaging.Current medicinal chemistry · 2025Review
- Supramolecular nanotherapeutics based on cucurbiturils.Journal of nanobiotechnology · 2024Review
- Room temperature phosphorescent wood hydrogel.Nature communications · 2024Article
- Study on the Influence of Host-Guest Structure and Polymer Introduction on the Afterglow Properties of Doped Crystals.Molecules (Basel, Switzerland) · 2024Article
- Urea-formaldehyde resin room temperature phosphorescent material with ultra-long afterglow and adjustable phosphorescence performance.Nature communications · 2024Article
- Cucurbit[8]uril-based supramolecular theranostics.Journal of nanobiotechnology · 2024Review
- Visible-light-excited robust room-temperature phosphorescence of dimeric single-component luminophores in the amorphous state.Nature communications · 2024Article
- Rapid room-temperature phosphorescence chiral recognition of natural amino acids.Nature communications · 2024Article
- Long lifetimes white afterglow in slightly crosslinked polymer systems.Nature communications · 2024Article
- Phosphorescent acyclic cucurbituril solid supramolecular multicolour delayed fluorescence behaviour.Chemical science · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purely organic room-temperature phosphorescence has attracted attention for bioimaging but can be quenched in aqueous systems. Here we report a water-soluble ultralong organic room-temperature phosphorescent supramolecular polymer by combining cucurbit[n]uril (CB[7], CB[8]) and hyaluronic acid (HA) as a tumor-targeting ligand conjugated to a 4-(4-bromophenyl)pyridin-1-ium bromide (BrBP) phosphor. The result shows that CB[7] mediated pseudorotaxane polymer CB[7]/HA-BrBP changes from small spherical aggregates to a linear array, whereas complexation with CB[8] results in biaxial pseudorotaxane polymer CB[8]/HA-BrBP which transforms to relatively large aggregates. Owing to the more stable 1:2 inclusion complex between CB[8] and BrBP and the multiple hydrogen bonds, this supramolecular polymer has ultralong purely organic RTP lifetime in water up to 4.33 ms with a quantum yield of 7.58%. Benefiting from the targeting property of HA, this supramolecular polymer is successfully applied for cancer cell targeted phosphorescence imaging of mitochondria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.