Evidence map›Paper›PMID 32938836›Full record

ArticleJournal of atherosclerosis and thrombosis2021

Japanese and Non-Japanese Patients with Transient Ischemic Attack or Minor Stroke: A Five-Year Risk Analysis of Stroke and Vascular Events.

Shinichiro Uchiyama, Takao Hoshino, Hugo Charles, Kenji Kamiyama, Taizen Nakase, Kazuo Kitagawa, Kazuo Minematsu, Kenichi Todo, Yasushi Okada, Jyoji Nakagawara and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Shinichiro UchiyamaClinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center.
Takao HoshinoDepartment of Neurology, Tokyo Women's Medical University.
Hugo CharlesDepartment of Neurology and Stroke Center, Bichat Hospital.
Kenji KamiyamaDepartment of Neurosurgery, Nakamura Memorial Hospital.
Taizen NakaseDepartment of Neurosurgery, Akita University.
Kazuo KitagawaDepartment of Neurology, Tokyo Women's Medical University.
Kazuo MinematsuNational Cerebral and Cardiovascular Center.
Kenichi TodoDepartment of Neurology, Osaka University Graduate School of Medicine.
Yasushi OkadaDepartment of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center.
Jyoji NakagawaraNational Cerebral and Cardiovascular Center.
Ken NagataYokohama General Hospital.
Hiroshi YamagamiDepartment of Stroke Neurology, National Hospital Organization Osaka National Hospital.
Takenori YamaguchiNational Cerebral and Cardiovascular Center.
Pierre AmarencoDepartment of Neurology and Stroke Center, Bichat Hospital.
National Cerebral and Cardiovascular Center · JPTokyo Women's Medical University · JPAkita University · JPBristol General Hospital · GBInternational University of Health and Welfare · JPNakamura Memorial Hospital · JPNational Kyushu Medical Center · JPOsaka National Hospital · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe have previously reported 5-year follow-up data on the TIAregistry.org, an international prospective cohort in patients with transient ischemic attack (TIA) or minor stroke. We conducted a Japanese subgroup analysis because outcomes and predictors might differ according to ethnicities and regions. In this study, we compared the baseline and 5-year follow-up data of Japanese and non-Japanese patients with TIA or minor stroke.

methodsPatients with TIA or minor ischemic stroke within 7 days after the onset were classified into two groups based on ethnicity, Japanese (n=345) and non-Japanese (n=3502); further, 5-year event rates were compared between the two groups. We also determined predictors of 5-year stroke for both groups.

resultsVascular death and death from any cause were identified to be less prevalent, unlike stroke and intracranial hemorrhage, which was determined to be more prevalent in Japanese than in non-Japanese patients. Five-year rate of stroke was significantly higher in Japanese patients. Cumulative stroke and major cardiovascular event rates did not decline but instead linearly increased from 1 to 5 years in both groups. Baseline risk factors for 5-year stroke were as follows: age, diabetes, history of stroke or TIA, and congestive heart failure in Japanese patients. Independent predictors of 5-year stroke were large artery atherosclerosis, congestive heart failure, diabetes, and age in Japanese patients.

conclusionsRecurrent stroke and intracranial hemorrhage were determined to be more prevalent at 5 years after TIA or minor stroke in Japanese patients than in non-Japanese patients. Strategies to mitigate the long-term risks of stroke, aside from adherence to current guidelines, should take Japanese-patient-specific residual risks into account.

Indexed as

Ischemic Attack, TransientIschemic StrokeRisk AssessmentAgedEthnicityFemaleFollow-Up StudiesHeart Disease Risk FactorsHumansJapanMalePrevalencePreventive Health ServicesPrognosisRecurrenceRegistriesOutcomePredictorRisk factorStrokeTransient ischemic attack

Identifiers

PMID32938836
PMCPMC8219541
OpenAlexW3087079518

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.