Evidence map›Paper›PMID 32938776›Full record

ReviewPediatrics2020

Trajectories of Lung Function in Infants and Children: Setting a Course for Lifelong Lung Health.

Brian K Jordan, Cindy T McEvoy

Open access · greenAbstract readReview
In one paragraph

Review in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Allergic sensitization and respiratory infection in infancy-Too early for two-hits on lung function?Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  5. Article
  6. Pulmonary function tests in the neonatal intensive care unit and beyond: a clinical review.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. The association of the room air challenge with long-term outcomes in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Role of Lung Function in Determining Which Children Develop Asthma.The journal of allergy and clinical immunology. In practice · 2023
    Article
  17. Article
  18. Article
  19. Air pollution as an early determinant of COPD.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brian K JordanDoernbecher Children's Hospital, Oregon Health & Science University, Portland, Oregon jordabr@ohsu.edu.
Cindy T McEvoyDoernbecher Children's Hospital, Oregon Health & Science University, Portland, Oregon.
Oregon Health & Science University · US

Funding

Maternal vitamin C supplementation to decrease effects of smoking during pregnancy on infant lung function and health:Follow-up of 2 randomized trials and association with changes in DNA methylationUH3OD023288 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia T McEvoy, ELIOT R SPINDEL · 2018 to 2026
$12.1M
Oregon Clinical and Translational Research Institute KL2 SupplementKL2TR002370 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Catherine Lee Hough · 2017 to 2026
$10.1M
VitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-CCC-LeadR01HL105447 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T · 2012 to 2021
$9.8M
CPAP Drives Lung Growth and Pulmonary Function in Moderately Preterm PrimatesR01HL129060 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T, SPINDEL, ELIOT R · 2015 to 2019
$3.9M
Trajectories of Lung Function in Extremely Premature InfantsK23HL144918 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI JORDAN, BRIAN K · 2019 to 2023
$819k
NCATS NIH HHS KL2 TR002370NHLBI NIH HHS K23 HL144918NHLBI NIH HHS R01 HL105447NHLBI NIH HHS R01 HL129060NIH HHS UH3 OD023288
6 · The paper itself

Abstract

For healthy individuals, it is increasingly accepted that lung function follows along an individual percentile established early in life and that the level of maximal function reached as a young adult can affect the subsequent development of lung disease that occurs with the normal aging process. This emphasizes the need to maximize early lung function. The trajectories of lung function are at least partially established by perinatal factors, including prematurity and in utero exposures (tobacco exposure, nutrition, inflammation, etc), although they can also be affected by a variety of additional factors and exposures throughout the life span. Whether lung function trajectories can be impacted or reset if established under suboptimal conditions is an unanswered question, offering new avenues for research. In this review, we will summarize important articles outlining lung function trajectories and linking pediatric lung function tests to adult lung function tests decades later. We will focus on perinatal factors and outline progress and opportunities for further investigation into the potential ability to reset trajectories to impact long-term lung health.

Indexed as

ChildFemaleHumansInfantInfant, PrematureInfant, Premature, DiseasesLungLung DiseasesPerinatal CarePregnancyPrenatal Exposure Delayed EffectsRespiratory Function Tests

Identifiers

PMID32938776
PMCPMC7546086
OpenAlexW3087105054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.