Evidence map›Paper›PMID 32938729›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

T Cells from NOD-

Jeremy J Racine, Harold D Chapman, Rosalinda Doty, Brynn M Cairns, Timothy J Hines, Abigail L D Tadenev, Laura C Anderson, Torrian Green, Meaghan E Dyer, Janine M Wotton and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Advancing Animal Models of Human Type 1 Diabetes.Cold Spring Harbor perspectives in medicine · 2024
    Review
  2. Article
  3. Role of the Intermediate Filament Protein Peripherin in Health and Disease.International journal of molecular sciences · 2022
    Review
  4. The NOD Mouse Beyond Autoimmune Diabetes.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Jeremy J RacineThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0001-5514-3074
Harold D ChapmanThe Jackson Laboratory, Bar Harbor, ME 04609.
Rosalinda DotyThe Jackson Laboratory, Bar Harbor, ME 04609.
Brynn M CairnsThe Jackson Laboratory, Bar Harbor, ME 04609.
Timothy J HinesThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0002-0594-7354
Abigail L D TadenevThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0003-0801-8267
Laura C AndersonThe Jackson Laboratory, Bar Harbor, ME 04609.
Torrian GreenThe Jackson Laboratory, Bar Harbor, ME 04609.
Meaghan E DyerThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0002-9908-4173
Janine M WottonThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0002-1899-9452
Zoë BichlerThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0003-1942-480X
Jacqueline K WhiteThe Jackson Laboratory, Bar Harbor, ME 04609.
Rachel EttingerViela Bio, Gaithersburg, MD 20878; and.ORCID 0000-0003-3761-9571
Robert W BurgessThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0002-9229-3407
David V SerrezeThe Jackson Laboratory, Bar Harbor, ME 04609; dave.serreze@jax.org.ORCID 0000-0001-7614-5925
Jackson Laboratory · USAstraZeneca (United States) · US

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
The Jackson Laboratory Center for Precision Genetics: From New Models to Novel TherapeuticsU54OD020351 · OD · JACKSON LABORATORY · PI LUTZ, CATHLEEN M · 2015 to 2019
$10.2M
Diabetogenic Role of MHC Class I Alleles in NOD MiceR01DK046266 · NIDDK · JACKSON LABORATORY · PI SERREZE, DAVID V · 2000 to 2018
$7.2M
B-lymphocyte Targeting Therapies for Autoimmune DiabetesR01DK095735 · NIDDK · JACKSON LABORATORY · PI SERREZE, DAVID V · 2013 to 2025
$6.2M
Genetics of the Neuromuscular Junction: Mechanisms and Disease ModelsR01NS054154 · NINDS · JACKSON LABORATORY · PI BURGESS, ROBERT W. · 2006 to 2019
$6.0M
The Genetics of the Neuromuscular Junction: Mechanisms and Disease ModelsR37NS054154 · NINDS · JACKSON LABORATORY · PI Robert W. Burgess · 2020 to 2026
$5.9M
Genetics of the Neuromuscular Junction: Mechanisms and Disease ModelsR56NS054154 · NINDS · JACKSON LABORATORY · PI BURGESS, ROBERT W. · 2015 to 2015
$613k
DIABETOGENIC ROLE OF H-2G7 CLASS I ALLELES IN NOD MICER29DK046266 · NIDDK · JACKSON LABORATORY · PI SERREZE, DAVID V. · 1993 to 1998
–
NCI NIH HHS P30 CA034196NIDDK NIH HHS R01 DK046266NIDDK NIH HHS R01 DK095735NIDDK NIH HHS R29 DK046266NIH HHS U54 OD020351NINDS NIH HHS R01 NS054154NINDS NIH HHS R37 NS054154NINDS NIH HHS R56 NS054154
6 · The paper itself

Abstract

It has become increasingly appreciated that autoimmune responses against neuronal components play an important role in type 1 diabetes (T1D) pathogenesis. In fact, a large proportion of islet-infiltrating B lymphocytes in the NOD mouse model of T1D produce Abs directed against the neuronal type III intermediate filament protein peripherin. NOD-

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Nerve TissueNeuritis, Autoimmune, ExperimentalPancreasAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesMiceMice, Inbred NODMice, SCIDMice, Transgenic

Identifiers

PMID32938729
PMCPMC7694871
OpenAlexW3087256087

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.