Evidence map›Paper›PMID 32938668›Full record

ArticleScience advances2020

Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP

Alvin Yu, Elizabeth M Y Lee, Jaehyeok Jin, Gregory A Voth

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Mechanisms of HIV-1 assembly, release and maturation.Nature reviews. Microbiology · 2026
    Review
  2. Voltage-sensor conformational microenvironments encode isoform-selective ion channel activation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Mechanism of HIV-1 Capsid Rupture and Uncoating by Reverse Transcription.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Kinetic implications of IPScience advances · 2025
    Article
  12. Article
  13. A conifer metabolite corrects episodic ataxia type 1 by voltage sensor-mediated ligand activation of Kv1.1.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Journal of chemical theory and computation · 2023
    Article
  16. Article
  17. Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Strain and rupture of HIV-1 capsids during uncoating.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alvin YuDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8051-7661
Elizabeth M Y LeePritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9143-3140
Jaehyeok JinDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-3859-3545
Gregory A VothDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637, USA. gavoth@uchicago.edu.ORCID 0000-0002-3267-6748

Funding

Virus TransmissionP50AI150464 · NIAID · UNIVERSITY OF UTAH · PI KAY, MICHAEL S · 2019 to 2021
$14.9M
Breakthrough Molecular Dynamics Research via an Anton2 SupercomputerR01GM116961 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BLOOD, PHILIP D. · 2016 to 2023
$3.0M
Computational and Theoretical Studies of Retroviral Replication - ResubmissionF32AI150208 · NIAID · UNIVERSITY OF CHICAGO · PI YU, ALVIN · 2020 to 2022
$147k
Theory and SImulation of Viral ReplicationK99AI167034 · NIAID · UNIVERSITY OF CHICAGO · PI YU, ALVIN · 2022 to 2022
$90k
NIAID NIH HHS F32 AI150208NIAID NIH HHS K99 AI167034NIAID NIH HHS P50 AI150464NIGMS NIH HHS R01 GM116961
6 · The paper itself

Abstract

Inositol hexakisphosphates (IP

Identifiers

PMID32938668
PMCPMC7494349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.