ArticleHealth and quality of life outcomes2020
Health-related quality of life became worse in short-term during treatment in head and neck cancer patients: a prospective study.
Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Effect of exercise across the head and neck cancer continuum: a systematic review of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Impact of Nutrition Counseling in Head and Neck Cancer Sufferers Undergoing Antineoplastic Therapy: A Randomized Controlled Pilot Study.Current oncology (Toronto, Ont.) · 2022Trial
- Depression Among Patients With Laryngeal Cancer: A Retrospective Cohort Study.Laryngoscope investigative otolaryngology · 2025Article
- Patient-reported outcomes in head and neck cancer: a cross-sectional analysis of quality of life domains across early and advanced UICC stages.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Self-perceived oral health, general self-efficacy, and their relations to oral health conditions in head and neck cancer patients in Sweden-a prospective observational study.Frontiers in oral health · 2025Article
- Prospective study on health-related quality of life, oral mucositis and oral health on during treatment of head and neck cancer.BMC oral health · 2024Article
- Quality of Life of Patients with Oral Squamous Cell Carcinoma.Iranian journal of public health · 2024Article
- Frailty is an independent factor for health-related quality of life in patients with head and neck cancer receiving definitive concurrent chemoradiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Two-year evolution of quality of life following radiotherapy and/or chemotherapy in patients with head and neck cancer.Asia-Pacific journal of oncology nursing · 2023Article
- Clinical and psychosocial factors associated with quality of life in patients with head and neck cancer: an analytical cross-sectional study from a lower-middle-income country.BMC psychology · 2023Article
- Quality of life in patients treated for COVID-19-associated mucormycosis at a tertiary care hospital.Osong public health and research perspectives · 2023Article
- Quality of Life, Psychological Distress, and Nutritional Status of Polish Patients with Head and Neck Cancer Treated with Radiotherapy.Journal of clinical medicine · 2023Article
- Article
- The Impact of AC and AC-T Chemotherapy's Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study.Breast cancer (Dove Medical Press) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuality of life (QoL) is influenced in head and neck cancer (HNC) patients by a set of factors related to diagnosis, treatment and tumor impacts. The aim of this study was to evaluate the Quality of Life (QoL) changes in Head and Neck cancer (HNC) patients during treatment (radiotherapy and/or chemoradiotherapy).
methodsQoL was evaluated prospectively in 63 HNC patients during radiotherapy and/or chemoradiotherapy at three moments: before or at beginning (T0), in the middle (T1 ~ four weeks) and immediately at the end (T2 ~ eight weeks) of treatment. The differences between the scores at different time points was verified using Friedman's non-parametric test. Negative changes between time points were evaluated, with differences (delta) of ±10 points being considered to be clinically significant.
resultsThe total mean age was 59.1 ± 9.5y, and 82.5% were male. The oral cavity and larynx were more frequent tumors. The functional score for 'role' was decreased at time points T1 and T2 as compared to T0, while an improvement in scores was observed for cognitive function. Several physical symptoms also worsened over time, such as: fatigue, nausea and vomiting, dry mouth and sticky saliva, swallowing and skin symptoms, senses and teeth problems. A high frequency of altered and clinically meaningful values were observed for most of domains, ranging from 6 to 74%.
conclusionsThe QoL became worse at approximately one month after treatment beginning in HNC patients, and this remained until the end of therapy. Protocols directing to early nutritional counseling and management of symptoms of nutritional impact are important to improve clinical outcomes. This is part of preventive actions aiming to make the exhausting treatment process less traumatic and easier to complete.
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