Evidence map›Paper›PMID 32938013›Full record

ArticleInternational journal of molecular sciences2020

Adenosine A2a Receptor Stimulation Attenuates Ischemia-Reperfusion Injury and Improves Survival in A Porcine Model of DCD Liver Transplantation.

Zoltan Czigany, Eve Christiana Craigie, Georg Lurje, Shaowei Song, Kei Yonezawa, Yuzo Yamamoto, Thomas Minor, René Hany Tolba

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. New Frontiers in Organ Preservation and Hepatoprotection.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Zoltan CziganyDepartment of Surgery and Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0003-0373-3210
Eve Christiana CraigieInstitute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH-Aachen University, 52074 Aachen, Germany.
Georg LurjeDepartment of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum-Charité-Universitätsmedizin, 13353 Berlin, Germany.ORCID 0000-0001-9674-0756
Shaowei SongDepartment of Surgery, The First Affiliated Hospital of China Medical University, Shenyang 110122, China.
Kei YonezawaDepartment of Surgery, Shizuoka City Hospital, Shizuoka 420-8527, Japan.
Yuzo YamamotoDepartment of Gastroenterological Surgery, Akita University Graduate School of Medicine, Akita 010-0825, Japan.ORCID 0000-0001-5178-9169
Thomas MinorDepartment of General, Visceral, and Transplantation Surgery, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0002-7124-3590
René Hany TolbaInstitute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH-Aachen University, 52074 Aachen, Germany.
RWTH Aachen University · DEAkita University · JPCharité - Universitätsmedizin Berlin · DEChina Medical University · CNEssen University Hospital · DEShizuoka City Hospital · JP

Funding

B.Braun Foundation, Melsungen, Germany BBST-S-17-00240Clinician Scientist Program Faculty of Medicine, RWTH Aachen University n.a.START Program Faculty of Medicine, RWTH Aachen University #23/19
6 · The paper itself

Abstract

Orthotopic liver transplantation (OLT) using allografts from donation after circulatory death (DCD) is potentially associated with compromised clinical outcomes due to ischemia-reperfusion injury (IRI)-induced organ damage and graft-related complications. The aim of this study was to provide in vivo data on the effects of adenosine A

Indexed as

AdenosineAdenosine A2 Receptor AgonistsAnimalsDisease Models, AnimalFemaleGlucoseLiverLiver TransplantationLiving DonorsMannitolOrgan PreservationOrgan Preservation SolutionsPhenethylaminesPotassium ChlorideProcaineReceptor, Adenosine A2A2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineAdenosineAdenosine A2 Receptor AgonistsBretschneider cardioplegic solutionGlucoseMannitolOrgan Preservation SolutionsPhenethylaminesPotassium ChlorideProcaineReceptor, Adenosine A2Aadenosine A2a agonistdonation after circulatory deathhepatoprotectionliver transplantationmicrocirculationporcine modelreperfusion injurysurvival

Identifiers

PMID32938013
PMCPMC7555737
OpenAlexW3086520663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.