Evidence map›Paper›PMID 32937963›Full record

ReviewBioengineering (Basel, Switzerland)2020

Biomimetic Nanocarriers for Cancer Target Therapy.

Clara Guido, Gabriele Maiorano, Barbara Cortese, Stefania D'Amone, Ilaria Elena Palamà

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  17. Article
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  19. pHEMA: An Overview for Biomedical Applications.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Clara GuidoDepartment of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.
Gabriele MaioranoNanotechnology Institute, CNR-NANOTEC, Monteroni Street, 73100 Lecce, Italy.ORCID 0000-0003-2205-2293
Barbara CorteseNanotechnology Institute, CNR-NANOTEC, c/o La Sapienza University, Piazzale A. Moro, 00185 Rome, Italy.ORCID 0000-0001-8667-7255
Stefania D'AmoneNanotechnology Institute, CNR-NANOTEC, Monteroni Street, 73100 Lecce, Italy.
Ilaria Elena PalamàNanotechnology Institute, CNR-NANOTEC, Monteroni Street, 73100 Lecce, Italy.ORCID 0000-0003-4420-0680

Funding

FISR project "Tecnopolo di Nanotecnologia e Fotonica per la Medicina di Precisione CUP B83B17000010001Progetto Tecnopolo per la Medicina di precisione, Delibera della Giunta Regionale n. 2117 del 21/11/2018" n. 2117 del 21/11/2018
6 · The paper itself

Abstract

Nanotechnology offers innovative tools for the design of biomimetic nanocarriers for targeted cancer therapy. These nano-systems present several advantages such as cargo's protection and modulation of its release, inclusion of stimuli-responsive elements, and enhanced tumoral accumulation. All together, these nano-systems suffer low therapeutic efficacy in vivo because organisms can recognize and remove foreign nanomaterials. To overcome this important issue, different modifications on nanoparticle surfaces were exploited in order to reach the desired therapeutic efficacy eliciting, also, the response of immune system against cancer cells. For this reason, more recently, a new strategy involving cell membrane-covered nanoparticles for biomedical application has been attracting increasing attention. Membranes from red blood cells, platelets, leukocytes, tumor, and stem cells, have been exploited as biomimetic coatings of nanoparticles for evading clearance or stimulated immune system by maintaining in the same way their targeting capability. In this review, the use of different cell sources as coating of biomimetic nanocarriers for cancer therapy is discussed.

Indexed as

biomimetic nanoparticlescancer therapyimmunotherapy

Identifiers

PMID32937963
PMCPMC7552783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.