ArticlePolymers2020
A Novel Approach to Increase the Oxygen Permeability of Soft Contact Lenses by Incorporating Silica Sol.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06995781 (A Multicenter, Randomized, Double-blind, Parallel, Controlled Study Assessing the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses), which is not on this map. Cited by 7 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Randomized, Double-blind, Parallel, Controlled Study Assessing the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3)
Who cites it
7 citing papers in PubMed.
- Recent Nanotechnological Trends in the Management of Microbial Keratitis.Journal of ophthalmic & vision research · 2024Review
- Optimization of the Oxygen Permeability of Non-Silicone Hydrogel Contact Lenses Through Crosslinking Modifications.Gels (Basel, Switzerland) · 2024Article
- Design Characteristics of a Neoteric, Superhydrophilic, Mechanically Robust Hydrogel Engineered To Limit Fouling in the Ocular Environment.ACS omega · 2024Article
- Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management.Chemical reviews · 2023Review
- Contact lens as an emerging platform for ophthalmic drug delivery: A systematic review.Asian journal of pharmaceutical sciences · 2023Review
- Recent Advances in Hydrogels for the Diagnosis and Treatment of Dry Eye Disease.Gels (Basel, Switzerland) · 2022Review
- Characterization of Biocompatible Hydrogel Lenses Using Methacrylic Acid with Neodymium Oxide Nanoparticles.Polymers · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This study presents a novel approach to increase the oxygen permeability of hydrogel by the addition of silica sol. Herein, 2-hydroxyethyl methacrylate (HEMA) was copolymerized with N-vinyl-2-pyrrolidone (NVP) after mixing with silica sol. The resultant hydrogel was subject to characterizations including Fourier-transform infrared (FTIR), equilibrium water content (EWC), contact angle, optical transmittance, oxygen permeability (Dk), tensile test, anti-deposition of proteins, and cytotoxicity. The results showed that with the increase of silica content, the Dk values and Young's moduli increased, the optical transmittance decreased slightly, whereas the EWC and contact angle, and protein deposition were not much affected. Moreover, the cytotoxicity of the resultant poly(HEMA-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.